HPE 64GB 2Rx4 PC5-4800B-R RDIMM SmartMemory

The HPE 64GB 2Rx4 PC5-4800B-R RDIMM SmartMemory (P43330-B21) is a DDR5-4800 registered ECC dual-rank module engineered specifically for HPE ProLiant Gen11 servers. Built on the DDR5 architecture, it operates at a native transfer rate of 4800 MT/s with a 288-pin RDIMM form factor, delivering substantially higher bandwidth and improved power efficiency compared to its DDR4 predecessors. The module integrates an on-die ECC layer combined with system-level ECC correction, providing multi-tiered data integrity protection essential for mission-critical enterprise environments.

HPE SmartMemory technology enables the server's Advanced Memory Protection and Advanced Memory Error Detection features to function at full capability, as the module contains an HPE-authenticated SPD that is recognized and validated by HPE ProLiant firmware. This firmware integration allows HPE Integrated Lights-Out (iLO) to report granular memory health data, enforce optimized memory configurations, and unlock platform-specific performance modes that are unavailable with non-SmartMemory modules. The 1.1 V operating voltage of DDR5 contributes to measurable reductions in thermal output per bit transferred relative to DDR4, a meaningful advantage in dense, high-core-count server deployments.

With a 64 GB capacity in a dual-rank (2Rx4) x4 device-width configuration, this module is well suited for memory-intensive workloads where large per-socket memory footprints are required. IT teams scaling AI inference pipelines, large in-memory databases, or virtualization hosts benefit from the higher aggregate bandwidth and improved channel efficiency that the DDR5-4800 standard provides. The module is validated for HPE ProLiant Gen11 platforms and is subject to HPE's rigorous compatibility and burn-in testing program, ensuring stable long-term operation in production datacenter environments.

Ideal for

• High-density VMware vSphere and Microsoft Hyper-V virtualization hosts requiring large per-socket memory capacity to support dozens of concurrent virtual machines
• In-memory databases such as SAP HANA, Oracle TimesTen, and Redis Enterprise where the entire working dataset must reside in RAM to meet sub-millisecond latency SLAs
• AI and machine learning inference servers that stage large model weights in system memory for rapid GPU or CPU-based inferencing across HPE ProLiant Gen11 platforms
• High-performance computing (HPC) clusters running memory-bandwidth-sensitive simulations in computational fluid dynamics, genomics, or financial risk modeling
• Enterprise ERP and CRM application servers consolidating multiple workloads onto a single ProLiant Gen11 node to reduce physical server count and operational overhead
• Datacenter infrastructure refresh projects replacing DDR4-based Gen10 systems with Gen11 platforms to achieve improved bandwidth-per-watt ratios and extended platform longevity

Technical specifications

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.