HPE 128GB 4Rx4 PC5-4800B-L LRDIMM SmartMemory

The HPE 128GB 4Rx4 PC5-4800B-L LRDIMM SmartMemory (P43332-B21) is a high-density DDR5 load-reduced dual inline memory module engineered for HPE ProLiant Gen11 servers. Operating at 4800 MT/s with a quad-rank, x4 organization, the module leverages an on-board data buffer to reduce the electrical load on the memory controller, enabling higher memory capacities per channel than standard RDIMMs while maintaining signal integrity at speed. The PC5-4800B-L designation confirms compliance with JEDEC DDR5 LRDIMM standards, and HPE SmartMemory firmware embedding allows the server's BIOS and iLO management subsystem to validate and optimize the module at boot, unlocking full platform-rated performance.

As a 128 GB LRDIMM operating on a 288-pin DDR5 interface with ECC, the module is purpose-built for memory-intensive enterprise and hyperscale workloads. The load-reduction buffer architecture makes it possible to populate all DIMM slots on multi-socket Gen11 platforms to reach multi-terabyte memory configurations, a critical requirement for in-memory databases, large virtualization pools, and AI/ML inference serving. HPE SmartMemory validation also enables proactive fault detection through the iLO Advanced memory health monitoring stack, distinguishing it from third-party alternatives that may operate at reduced speeds or without full iLO telemetry integration.

The P43332-B21 is designed specifically for HPE ProLiant Gen11 platforms including the DL380 Gen11, DL360 Gen11, DL560 Gen11, and ML350 Gen11, where it is recognized natively without requiring manual SPD overrides. Its combination of high per-DIMM capacity, DDR5 bandwidth, and HPE platform validation makes it a foundational building block for datacenter consolidation, AI infrastructure scaling, and mission-critical transactional workloads demanding both density and reliability.

Ideal for

• In-memory database deployments (SAP HANA, Oracle TimesTen) requiring maximum per-server memory capacity with full ECC protection
• Large-scale VMware vSphere or Red Hat OpenShift virtualization hosts where high DIMM density reduces physical server count across the datacenter
• AI and machine learning inference servers that benefit from high DDR5 bandwidth and large memory footprints to hold models and datasets in-memory
• High-performance computing (HPC) clusters running memory-bound simulation and modeling workloads on HPE ProLiant Gen11 nodes
• Enterprise data warehousing and analytics platforms using columnar databases that stage large working sets entirely in RAM
• Cloud service provider infrastructure buildouts requiring validated, platform-integrated memory modules with iLO health monitoring for predictive fault management

Technical specifications

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.