HPE 64GB (1x64GB) DDR5-5600 CAS-46 Dual Rank x4 Registered Smart Memory Kit

HPE 64GB (1x64GB) DDR5-5600 CAS-46 Dual Rank x4 Registered Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: P64340-B21 | Part #: P64340-B21 | MPN: P64340-B21

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About the HPE 64GB (1x64GB) DDR5-5600 CAS-46 Dual Rank x4 Registered Smart Memory Kit

The HPE 64GB (1x64GB) DDR5-5600 CAS-46 Dual Rank x4 Registered Smart Memory Kit (P64340-B21) is a high-capacity, high-frequency server memory module engineered for HPE ProLiant Gen11 platforms. Built on the DDR5 architecture, it operates at 5600 MT/s with a CAS latency of 46, delivering the elevated memory bandwidth and improved power efficiency that modern datacenter, AI inference, and high-performance computing workloads demand. The Registered (RDIMM) design with dual rank x4 organization enhances signal integrity across multi-DIMM configurations, enabling stable operation in densely populated memory channels.

As an HPE Smart Memory module, this kit incorporates an integrated Serial Presence Detect (SPD) and a platform-aware identification system that allows HPE servers to recognize and validate the module at POST, unlocking full platform performance and enabling advanced RAS (Reliability, Availability, and Serviceability) features. This includes support for On-Die ECC, which catches and corrects single-bit errors within the DRAM die itself before they propagate, and compatibility with higher-level system ECC implementations supported by the host platform. The x4 die width further strengthens error correction coverage compared to x8 configurations.

With 64GB of capacity in a single DIMM, this module is well-suited for memory-intensive enterprise environments where maximizing per-slot density reduces the number of DIMMs required while achieving high total memory capacity per server node. It is specifically validated and optimized for HPE Gen11 server platforms, ensuring firmware-level compatibility, thermal management, and memory subsystem tuning aligned with HPE's quality and performance standards for production datacenter deployments.

Ideal for

  • In-memory database hosting and real-time analytics platforms requiring high per-node memory capacity and bandwidth, such as SAP HANA or Oracle Database In-Memory on HPE ProLiant Gen11 servers
  • AI and machine learning inference workloads where large model footprints and rapid data throughput benefit from DDR5-5600 bandwidth and high-density 64GB DIMMs
  • Virtualization infrastructure running large numbers of concurrent VMs on VMware vSphere or Microsoft Hyper-V, where maximizing total usable memory per host is critical for consolidation ratios
  • High-performance computing clusters executing memory-bound parallel workloads in scientific research, financial modeling, or engineering simulation environments
  • Enterprise application servers running ERP, CRM, or business intelligence platforms that require large working memory sets and continuous availability with ECC protection
  • Cloud service provider and hyperscale datacenter nodes where DDR5 power efficiency advantages reduce operational energy consumption at scale across high-density server deployments

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP64340-B21
Module Capacity64GB
Kit Configuration1x64GB
Memory TechnologyDDR5
Memory Speed5600 MT/s
CAS Latency46 (CL46)
Module TypeRDIMM (Registered DIMM)
RankDual Rank
DRAM Die Widthx4
Error CorrectionECC with On-Die ECC (ODECC)
Form Factor288-pin DIMM
Voltage1.1V
Memory GenerationDDR5
Platform CompatibilityHPE ProLiant Gen11
Smart MemoryYes — HPE Smart Memory with platform validation at POST
Module Quantity in Kit1

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryMemory (RAM)
SKUP64340-B21
Part NumberP64340-B21
ConditionNew
Manufacturer Part NumberP64340-B21
Module Capacity64GB
Kit Configuration1x64GB
Memory TechnologyDDR5
Memory Speed5600 MT/s
CAS Latency46 (CL46)
Module TypeRDIMM (Registered DIMM)
RankDual Rank
DRAM Die Widthx4
Error CorrectionECC with On-Die ECC (ODECC)
Form Factor288-pin DIMM
Voltage1.1V
Memory GenerationDDR5
Platform CompatibilityHPE ProLiant Gen11
Smart MemoryYes — HPE Smart Memory with platform validation at POST
Module Quantity in Kit1

Frequently Asked Questions about HPE 64GB (1x64GB) DDR5-5600 CAS-46 Dual Rank x4 Registered Smart Memory Kit

Is the HPE 64GB (1x64GB) DDR5-5600 CAS-46 Dual Rank x4 Registered Smart Memory Kit compatible with my server?

Part number P64340-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.

What support applies to this memory module?

Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.

How do I request a quote?

Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.