HPE 16GB (1x16GB) DDR5-5600 CAS-46 Single Rank x8 Registered Smart Memory Kit

HPE 16GB (1x16GB) DDR5-5600 CAS-46 Single Rank x8 Registered Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: P64342-B21 | Part #: P64342-B21 | MPN: P64342-B21

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About the HPE 16GB (1x16GB) DDR5-5600 CAS-46 Single Rank x8 Registered Smart Memory Kit

The HPE 16GB (1x16GB) DDR5-5600 CAS-46 Single Rank x8 Registered Smart Memory Kit (P64342-B21) delivers next-generation DDR5 memory performance engineered specifically for HPE ProLiant Gen11 server platforms. Operating at 5600 MT/s with a CAS latency of 46, this registered DIMM (RDIMM) module leverages the DDR5 architecture's on-die ECC, improved power efficiency through integrated voltage regulation (PMIC), and doubled memory channels compared to DDR4, enabling substantially higher memory bandwidth for demanding server workloads.

As a Single Rank x8 configuration, this kit is optimized to balance capacity, signal integrity, and compatibility across a broad range of HPE Gen11 platforms. HPE Smart Memory technology embeds an on-module Serial Presence Detect (SPD) that enables the server firmware to identify, validate, and unlock platform-specific performance features — including Advanced Memory Protection (AMP) modes such as Advanced ECC — ensuring the module is recognized as a HPE component and operates at its rated DDR5-5600 speed within supported platforms.

This module is purpose-built for enterprise datacenters, AI/ML inference infrastructure, high-performance computing environments, and virtualization hosts where memory bandwidth, density scalability, and validated platform integration are critical. It operates at 1.1V, reducing power consumption relative to equivalent DDR4 implementations, supporting sustainability objectives in modern datacenter deployments. Omnixon Global supplies this module to enterprise and public sector buyers across the UAE, GCC, EMEA, and APAC regions.

Ideal for

  • High-density VMware vSphere or Microsoft Hyper-V virtualization hosts requiring validated, high-bandwidth DDR5 memory to support increased VM-per-host ratios on HPE ProLiant Gen11 servers
  • AI inference and machine learning serving nodes where DDR5-5600 memory bandwidth accelerates data throughput between CPUs and accelerators in edge or rack-scale deployments
  • In-memory database platforms such as SAP HANA or Redis running on HPE Gen11 servers, where memory speed and Advanced ECC protection are essential for data integrity and performance
  • Enterprise private cloud infrastructure buildouts requiring large quantities of standardized, HPE-validated DDR5 DIMMs with predictable platform compatibility across homogeneous server fleets
  • High-performance computing (HPC) clusters processing scientific, financial modeling, or simulation workloads that benefit from the increased memory bandwidth and lower latency of DDR5-5600
  • Enterprise VDI (Virtual Desktop Infrastructure) environments on HPE Gen11 platforms where higher memory throughput supports increased concurrent user sessions per physical host

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP64342-B21
Module TypeRDIMM (Registered DIMM)
Memory TechnologyDDR5
Capacity16GB
Kit Configuration1 x 16GB
Memory Speed5600 MT/s (DDR5-5600)
CAS LatencyCL46
Rank ConfigurationSingle Rank
DRAM Bus Widthx8
Operating Voltage1.1V
Error CorrectionECC (with on-die ECC and Advanced ECC support via HPE AMP)
Form Factor288-pin DIMM
HPE Smart MemoryYes — platform-validated with SPD for automatic recognition and feature unlock on HPE ProLiant Gen11 servers
Compatible Platform GenerationHPE ProLiant Gen11
On-Die ECCYes (DDR5 native)
Power Management ICIntegrated PMIC (DDR5 standard)

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryMemory (RAM)
SKUP64342-B21
Part NumberP64342-B21
ConditionNew
Manufacturer Part NumberP64342-B21
Module TypeRDIMM (Registered DIMM)
Memory TechnologyDDR5
Capacity16GB
Kit Configuration1 x 16GB
Memory Speed5600 MT/s (DDR5-5600)
CAS LatencyCL46
Rank ConfigurationSingle Rank
DRAM Bus Widthx8
Operating Voltage1.1V
Error CorrectionECC (with on-die ECC and Advanced ECC support via HPE AMP)
Form Factor288-pin DIMM
HPE Smart MemoryYes — platform-validated with SPD for automatic recognition and feature unlock on HPE ProLiant Gen11 servers
Compatible Platform GenerationHPE ProLiant Gen11
On-Die ECCYes (DDR5 native)
Power Management ICIntegrated PMIC (DDR5 standard)

Frequently Asked Questions about HPE 16GB (1x16GB) DDR5-5600 CAS-46 Single Rank x8 Registered Smart Memory Kit

Is the HPE 16GB (1x16GB) DDR5-5600 CAS-46 Single Rank x8 Registered Smart Memory Kit compatible with my server?

Part number P64342-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.

What support applies to this memory module?

Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.

How do I request a quote?

Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.