HPE 16GB DDR5-4800 Registered Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: HPEP43322B2116GBDDR54800RDIMM | Part #: P43322-B21 | MPN: P43322-B21

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HPE's 16GB DDR5-4800 Registered Smart Memory Kit (part number P43322-B21) is engineered for Intel Xeon Scalable 6th generation and newer platforms, where it occupies a single memory channel slot in your server architecture. This module brings DDR5 performance to mission-critical infrastructure at a capacity sweet spot—large enough to support demanding workloads without the cost multiplication of larger DIMM configurations. For data centre operators, storage architects, and enterprise infrastructure teams provisioning new generation compute, this HPE memory module represents a practical entry point into DDR5 technology without overcommitting budget on oversized capacity.

The P43322-B21 operates at 4800 MT/s with a nominal voltage of 1.1V, delivering the bandwidth modern server CPUs expect while maintaining the power efficiency that matters in large-scale deployments. DDR5 architecture fundamentally differs from DDR4 in its channel design and voltage regulation; HPE's implementation here includes on-DIMM voltage regulators that allow finer control over power delivery. This registered DIMM design—sometimes called buffered memory—isolates the address and control signals from the actual memory chips through a register layer, reducing electrical load on the CPU and enabling configurations with higher module counts. For HPE platform deployments where you're planning 12, 16, or more DIMMs per socket, registered memory prevents signal integrity degradation that would otherwise limit your ability to populate all available slots.

Error-Correcting Code (ECC) functionality comes standard on this HPE module, a non-negotiable requirement in enterprise environments where silent data corruption could cascade into application failures, financial loss, or compliance violations. ECC memory detects and corrects single-bit errors in real time without requiring intervention, and it logs multi-bit error events so your infrastructure team can identify failing hardware before catastrophic failure occurs. In regulated industries—financial services, healthcare, government—ECC is often a contractual mandate; in data centres running AI training jobs or complex analytics, a single bit flip in training data can invalidate weeks of computational work. HPE includes ECC on virtually all server memory it produces, and this 16GB DDR5 module is no exception.

Physical form factor matters less to most buyers than compatibility, but HPE's specification of UDIMM (unbuffered) form factor designation alongside the registered functionality reflects the generational overlap in server platforms during the DDR5 transition. The module is validated exclusively for HPE servers and workstations—ProLiant Gen11 and later, Synergy compute modules, and compatible Apollo systems. If you're refreshing infrastructure in mixed-vendor environments, verify platform support before ordering; HPE's memory validation process is strict, and non-validated combinations can create thermal, timing, or reliability issues. Omnixon Global maintains live inventory of HPE memory across multiple capacities and speed grades, and our technical team can confirm compatibility against your specific chassis and processor configuration before you commit to procurement.

System administrators and infrastructure planners choosing between DDR5 capacity options often face the decision between one large DIMM per channel or multiple smaller ones. The 16GB single-module approach (P43322-B21 supplies 1x16GB) offers simplicity for smaller deployments, redundancy benefits if you're mixing capacity tiers, and lower initial spend compared to 32GB or 64GB modules. A full platform might require six or eight of these modules depending on socket count and memory lane configuration, making the arithmetic straightforward for procurement teams. HPE's Smart Memory technology baked into this kit enables automatic configuration management—the memory identifies its own speed, latency, and voltage parameters to the system firmware, eliminating manual BIOS tuning and reducing deployment time.

Memory Performance and Configuration Specifications

• DDR5-4800 MT/s speed grade with 1.1V nominal operating voltage for Intel Xeon Scalable 6th generation and newer processors
• Registered DIMM (RDIMM) architecture with integrated voltage regulators, supporting higher module densities per socket without signal degradation
• Full ECC protection with real-time single-bit error correction and multi-bit error logging for compliance and reliability
• Single 16GB module per kit (P43322-B21) provides flexible capacity scaling for mixed-size deployments
• HPE Smart Memory auto-detection eliminates manual speed, latency, and voltage configuration in firmware
• Validated for HPE ProLiant Gen11, Synergy, and Apollo systems exclusively—requires confirmation for non-HPE platforms
• 1.1V low voltage operation reduces power consumption per module, supporting larger aggregate memory footprints with lower thermal load
• UDIMM form factor with registered control layer balances electrical stability across 6+ DIMM per socket configurations

Omnixon Global stocks HPE memory modules across the full DDR5 speed and capacity range, including the P43322-B21, for immediate delivery throughout the UAE, GCC region, and supporting customers across Asia and Europe. Whether you're qualifying memory for a pilot data centre build, expanding an existing HPE infrastructure, or provisioning memory for refresh cycles, our technical team works with your procurement and infrastructure groups to validate configurations, manage lead times, and ensure compatibility before deployment. Contact Omnixon Global for an RFQ on HPE 16GB DDR5-4800 Registered Smart Memory and all related server platform components.