HPE 64GB DDR5-4800 Registered Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: HPEP43331B2164GBDDR54800RDIMM | Part #: P43331-B21 | MPN: P43331-B21

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The HPE 64GB DDR5-4800 Registered Smart Memory Kit (part number P43331-B21) delivers 64GB capacity at 4800 MT/s in a single 1x64GB DIMM form factor, designed specifically for HPE's latest generation server and workstation platforms. This is the memory module that infrastructure teams reach for when they need to populate high-density compute nodes without fragmenting their DIMM slots or complicating sparing strategies. The DDR5 generation at 4800 MHz represents a meaningful step forward in per-socket bandwidth, particularly for workloads that push consistent throughput demands across multiple CPU cores.

HPE engineered this kit as a registered, buffered module with full ECC support, which means the part number P43331-B21 is built for mission-critical environments where data integrity cannot be compromised. The registered architecture isolates the memory controller from the DIMM's address and control lines, reducing electrical load on the CPU and improving stability in multi-socket configurations. The 1.1V operating voltage is optimized for power efficiency without sacrificing reliability, a balance that matters when you're running dual- or quad-socket systems that may host 20, 30, or more DIMMs across multiple nodes. Infrastructure architects and senior system administrators are the primary buyers of this module; they need single large-capacity DIMMs to maximize memory density without forcing costly slot trade-offs later.

Compatibility with HPE's server portfolio—including the ProLiant Gen11 systems and comparable workstation lines—is absolute. This is not a generic DDR5 stick from a third-party vendor; HPE has validated the P43331-B21 against their own platform requirements, ensuring that timing, voltage regulation, and error correction work as HPE's firmware expects. For organizations standardizing on HPE infrastructure across data centres, this validated pairing eliminates the guesswork and compatibility risk that can arise when mixing memory vendors. The single-module design also simplifies inventory management: one part number, one qualification process, one supplier chain to manage.

Deployment scenarios for the HPE 64GB DDR5-4800 Registered Smart Memory Kit span high-performance compute clusters, virtualization hosts requiring substantial guest memory overhead, database servers optimized for in-memory operations, and AI infrastructure setups where per-socket memory capacity directly impacts model serving density. Teams building out inference clusters or fine-tuning pipelines appreciate the efficiency gain of DDR5 bandwidth combined with the reliability guarantees of registered ECC memory. In virtualized environments, this module allows hypervisors to support more concurrent workloads per physical node without memory becoming the limiting factor. Data centre operators and procurement managers working toward capacity planning typically benchmark their actual workload memory utilization first, then size their HPE node purchases in multiples of this capacity to match that demand.

Omnixon Global stocks the HPE 64GB DDR5-4800 Registered Smart Memory Kit as part of our comprehensive HPE memory and server component portfolio serving data centres, AI labs, and enterprise IT teams across the UAE, GCC, and beyond. Whether you are building a new cluster, refreshing legacy infrastructure, or responding to urgent capacity demands, we maintain regional stock and can accelerate delivery across our established logistics network. Please submit an RFQ through our website or contact our technical sales team directly—we are here to support your infrastructure investments with the validated components and expert guidance your team requires.

Performance Specifications and Operating Parameters

• Capacity: 64GB single DIMM, eliminating the need for multi-module configurations in many HPE platforms
• Memory Speed: 4800 MT/s DDR5, delivering higher aggregate bandwidth than previous DDR4 generations
• Error Correction: Full ECC support with registered buffering for enterprise-grade data integrity
• Operating Voltage: 1.1V, optimized for thermal efficiency and reduced power draw in high-density deployments
• Form Factor: Standard DIMM design fitting all qualified HPE server and workstation platforms
• Part Number: P43331-B21 for definitive ordering and inventory tracking
• Validation: HPE factory-qualified to ensure firmware compatibility and performance consistency