HPE AMD Instinct MI300X 192GB OAM GPU Accelerator

HPE AMD Instinct MI300X 192GB OAM GPU Accelerator

Brand: HPE | Category: GPUs

SKU: P64568-B21 | Part #: P64568-B21 | MPN: P64568-B21

Contact for Pricing — Request a Quote

Request a Quote Contact Us

About the HPE AMD Instinct MI300X 192GB OAM GPU Accelerator

The HPE AMD Instinct MI300X 192GB OAM GPU Accelerator (P64568-B21) is built on AMD's CDNA 3 architecture, combining CPU and GPU compute dies with high-bandwidth memory in a unified chiplet design. The accelerator integrates 192GB of HBM3 memory across eight stacks, delivering up to 5.3 TB/s of aggregate memory bandwidth — a defining advantage for memory-bound AI inference and large-scale model training workloads. The OAM (OCP Accelerator Module) form factor ensures compatibility with open-standard AI accelerator platforms and high-density server configurations designed for modern datacenter deployments.

With 304 compute units and a peak FP16/BF16 throughput of 1.307 PFLOPS, the MI300X is engineered to handle the most demanding generative AI, large language model (LLM), and high-performance computing (HPC) tasks at enterprise scale. The massive unified memory pool eliminates the need for model sharding across multiple accelerators for many frontier-scale models, reducing system complexity and improving inference latency. Support for FP8, FP16, BF16, FP32, FP64, and INT8 precisions provides flexibility across training and inference pipelines.

As an HPE-branded component, the MI300X OAM accelerator is validated and integrated into HPE's enterprise server and AI infrastructure portfolio, including HPE Cray XD and ProLiant platforms designed for AI factories and exascale-class compute environments. The ROCm open software ecosystem provides a comprehensive, vendor-neutral foundation for AI/ML frameworks including PyTorch, TensorFlow, and JAX, enabling enterprises to build and scale AI workloads without proprietary software lock-in.

Ideal for

  • Large language model (LLM) training and fine-tuning, where the 192GB unified HBM3 memory pool accommodates multi-billion parameter models on fewer accelerators
  • Generative AI inference serving for production deployments requiring low latency and high throughput across text, image, and multimodal models
  • High-performance computing (HPC) simulations in scientific research, computational fluid dynamics, and molecular dynamics where FP64 double-precision performance is critical
  • Enterprise AI factory buildouts requiring open-standard OAM form factor accelerators within high-density, scalable rack architectures
  • Multi-node distributed training workloads leveraging high-bandwidth interconnects across HPE Cray XD supercomputing platforms
  • Data analytics and numerical computing pipelines requiring sustained memory bandwidth and broad floating-point precision support across mixed-precision workloads

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP64568-B21
Product NameHPE AMD Instinct MI300X 192GB OAM GPU Accelerator
GPU ArchitectureAMD CDNA 3
Form FactorOAM (OCP Accelerator Module)
Memory Capacity192 GB HBM3
Memory Bandwidth5.3 TB/s
HBM Stacks8
Compute Units304
Peak FP16 Performance1,307 TFLOPS
Peak BF16 Performance1,307 TFLOPS
Peak FP8 Performance2,614 TFLOPS
Peak FP64 Performance163.4 TFLOPS
Supported PrecisionsFP8, FP16, BF16, FP32, FP64, INT8
Thermal Design Power (TDP)750 W
InterconnectAMD Infinity Fabric
Software EcosystemAMD ROCm open software platform
Compatible FrameworksPyTorch, TensorFlow, JAX
Target PlatformHPE Cray XD, HPE ProLiant AI-optimized servers
Product CategoryGPU Accelerator

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryGPUs
SKUP64568-B21
Part NumberP64568-B21
ConditionNew
Manufacturer Part NumberP64568-B21
Product NameHPE AMD Instinct MI300X 192GB OAM GPU Accelerator
GPU ArchitectureAMD CDNA 3
Form FactorOAM (OCP Accelerator Module)
Memory Capacity192 GB HBM3
Memory Bandwidth5.3 TB/s
HBM Stacks8
Compute Units304
Peak FP16 Performance1,307 TFLOPS
Peak BF16 Performance1,307 TFLOPS
Peak FP8 Performance2,614 TFLOPS
Peak FP64 Performance163.4 TFLOPS
Supported PrecisionsFP8, FP16, BF16, FP32, FP64, INT8
Thermal Design Power (TDP)750 W
InterconnectAMD Infinity Fabric
Software EcosystemAMD ROCm open software platform
Compatible FrameworksPyTorch, TensorFlow, JAX
Target PlatformHPE Cray XD, HPE ProLiant AI-optimized servers
Product CategoryGPU Accelerator

Frequently Asked Questions about HPE AMD Instinct MI300X 192GB OAM GPU Accelerator

What server platforms accept the HPE AMD Instinct MI300X 192GB OAM GPU Accelerator?

Reference servers include Dell PowerEdge XE9680 / XE9712, HPE Cray XD670, Lenovo ThinkSystem SR685a / SR675 V3, Supermicro AS-A21GE / SYS-821GE, Gigabyte G593 / G894, ASUS ESC. Share your target platform in the RFQ and we will confirm chassis-to-GPU compatibility and recommended NIC pairing.

How long is the lead time on AI GPUs?

Highly model-dependent. L40S / RTX-class: typically 3-6 weeks. H100/H200/B200 in SXM form factor: 12-16 weeks for whole-platform allocations. We quote genuine-channel ETAs only — no grey-market promises.

Do you supply matched networking (Quantum InfiniBand / Spectrum-X)?

Yes — Omnixon stocks the full NVIDIA networking lineup (Quantum-2 / Quantum-X InfiniBand, Spectrum-X Ethernet, ConnectX NICs, BlueField DPUs) so we can quote a complete training-cluster BOM, not just the GPUs.

Can you help with NVIDIA AI Enterprise licensing?

Yes. We hold genuine-channels for NVIDIA AI Enterprise software subscriptions. Add it to your RFQ and we quote node-aligned licensing along with the hardware.