HPE ProLiant ML350 Gen12

The HPE ProLiant ML350 Gen12 represents the latest evolution of HPE's mid-range tower server platform, architected around the Intel Xeon 6 processor family and a next-generation DDR5 memory subsystem. The Gen12 platform introduces a redesigned system architecture that delivers significantly higher memory bandwidth and core density compared to its predecessor, enabling organizations to consolidate more workloads onto a single tower footprint without sacrificing performance headroom. The server supports both performance-core (P-core) and efficient-core (E-core) variants of the Intel Xeon 6 lineup, offering flexibility to match processor selection to the specific compute and throughput demands of each deployment site.

Targeted at branch offices, remote sites, and distributed enterprise environments, the ML350 Gen12 is optimized for deployments where rack infrastructure may not be available or practical, yet local compute capability is essential for latency-sensitive applications, edge analytics, and business continuity workloads. The platform features HPE's iLO 7 baseboard management controller, delivering advanced remote management, zero-touch provisioning, and hardware-level security including silicon root of trust — capabilities critical for IT teams managing distributed infrastructure with limited on-site personnel. The tower chassis design accommodates tool-less component access and hot-plug drive bays, reducing maintenance complexity in environments without dedicated data center staff.

The ML350 Gen12 integrates HPE Alletra storage connectivity options, broad PCIe Gen 5.0 expansion, and support for NVMe-based storage tiers, making it capable of handling virtualization stacks, software-defined networking appliances, database services, and file and print services simultaneously. Its power subsystem includes support for high-efficiency titanium-class redundant power supplies, and the platform is compatible with HPE GreenLake cloud services for unified management across hybrid environments. The Gen12 architecture also introduces enhanced accelerator support, enabling GPU or FPGA co-processors for inference and edge AI workloads at the branch level.

Ideal for

• Branch office virtualization hosting multiple VMs for local ERP, CRM, and collaboration services with resilience independent of WAN connectivity
• Remote site database server running Microsoft SQL Server or PostgreSQL for low-latency transactional workloads close to end users
• Edge AI inference platform leveraging GPU or accelerator cards for real-time image recognition, anomaly detection, or predictive maintenance at distributed industrial sites
• Software-defined networking and SD-WAN appliance hosting, consolidating network functions onto a single compute node in sites without dedicated rack space
• File, print, and directory services node for mid-sized branch offices requiring Active Directory, DNS, DHCP, and NAS capabilities in a compact tower form factor
• Backup and disaster recovery target node providing local data protection and rapid restore capabilities for branch-critical workloads with replication to central data centers

Technical specifications

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.