HPE ProLiant Compute XD685 Server

HPE ProLiant Compute XD685 Server

Brand: HPE | Category: Servers

SKU: HPE-P63500B21 | Part #: P63500-B21 | MPN: P63500-B21

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About the HPE ProLiant Compute XD685 Server

The HPE ProLiant Compute XD685 is a purpose-built, high-density accelerated compute server designed to meet the rigorous demands of generative AI training, large language model development, and deep learning at enterprise and hyperscale levels. The system is architected around an eight-GPU configuration, supporting either the NVIDIA HGX H200 SXM5 platform with NVLink interconnect or the AMD Instinct MI325X accelerators, giving organizations flexibility to align their AI infrastructure investment with their preferred GPU ecosystem. The server is designed for rack-dense deployment within HPE's broader AI Supercomputing portfolio, integrating seamlessly with HPE Cray networking and storage fabrics for end-to-end AI cluster buildouts.

At its core, the XD685 leverages AMD EPYC processors to deliver the PCIe bandwidth, memory capacity, and I/O throughput required to keep eight high-performance accelerators fully fed. The system supports high-bandwidth NVLink or Infinity Fabric interconnects between GPUs depending on the accelerator configuration, enabling collective operations and model-parallel training to scale efficiently across nodes. HPE's thermal and power delivery architecture is engineered to sustain the extreme power envelopes associated with eighth-generation GPU accelerators, incorporating advanced direct liquid cooling readiness and high-efficiency power supply redundancy.

The XD685 is a central building block for organizations constructing on-premises AI supercomputing clusters, national AI research infrastructure, and enterprise AI factories. Its integration with HPE GreenLake for HPC and AI provides a consumption-based operational model, while HPE's Integrated Lights-Out (iLO) management delivers deep telemetry, remote management, and security root-of-trust capabilities. The platform is validated for deployment with HPE Slingshot high-speed interconnect fabric, enabling low-latency, high-bandwidth GPU-to-GPU communication across multi-rack AI training clusters essential for frontier model development.

Ideal for

  • Training large language models and transformer-based foundation models requiring sustained multi-node GPU parallelism across thousands of accelerators
  • Generative AI model development including diffusion models, multimodal AI, and reinforcement learning from human feedback pipelines at enterprise scale
  • National and institutional AI research supercomputing clusters requiring dense GPU packing per rack unit with high-speed fabric connectivity
  • Enterprise AI factories running simultaneous fine-tuning workloads across multiple business units with shared accelerated infrastructure
  • High-performance scientific simulation and computational fluid dynamics workloads that benefit from GPU-accelerated numerical solvers
  • Financial services AI platforms performing large-scale risk modeling, fraud detection training, and quantitative research requiring GPU-accelerated compute

Technical specifications

ManufacturerHPE
Product LineHPE ProLiant Compute XD685
Form Factor4U Rack Server
Processor FamilyAMD EPYC (Genoa/Bergamo generation)
Processor Sockets2
GPU Configuration8x GPU accelerator slots (full SXM5/OAM form factor)
Supported GPU PlatformsNVIDIA HGX H200 SXM5 (NVLink 4.0) or AMD Instinct MI325X (Infinity Fabric)
GPU Memory (NVIDIA HGX H200)8x 141 GB HBM3e per node (1,128 GB total GPU memory)
GPU Memory (AMD MI325X)8x 256 GB HBM3e per node (2,048 GB total GPU memory)
GPU Interconnect BandwidthUp to 900 GB/s bidirectional per GPU (NVLink 4.0 / Infinity Fabric)
System Memory TypeDDR5 RDIMM / 3DS RDIMM
System Memory Slots24 DIMM slots (12 per processor)
Maximum System MemoryUp to 6 TB DDR5
Storage BaysUp to 12x NVMe SSD (front accessible)
Network Fabric SupportHPE Slingshot 200Gb/s Ethernet / HDR InfiniBand; front-end Ethernet via OCP NIC 3.0 slot
PCIe GenerationPCIe Gen 5.0
Power SupplyRedundant Titanium-level high-efficiency PSUs (N+1 or 2+2 configuration)
Power InputAC 200–240V; DC option available
CoolingHigh-velocity forced-air cooling; direct liquid cooling (DLC) ready
ManagementHPE iLO 6 (Integrated Lights-Out) with hardware root-of-trust, telemetry streaming, and zero-trust security architecture
Operating System SupportRed Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu Server LTS, Rocky Linux
Cluster Software IntegrationHPE Cray Programming Environment, Slurm, PBS Pro, Kubernetes with GPU Operator
Platform Launch2025 Q2
Standards ComplianceASHRAE A2/W35 thermal specifications; IEC, UL, CE safety certifications

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryServers
SKUHPE-P63500B21
Part NumberP63500-B21
ConditionNew
Product LineHPE ProLiant Compute XD685
Form Factor4U Rack Server
Processor FamilyAMD EPYC (Genoa/Bergamo generation)
Processor Sockets2
GPU Configuration8x GPU accelerator slots (full SXM5/OAM form factor)
Supported GPU PlatformsNVIDIA HGX H200 SXM5 (NVLink 4.0) or AMD Instinct MI325X (Infinity Fabric)
GPU Memory (NVIDIA HGX H200)8x 141 GB HBM3e per node (1,128 GB total GPU memory)
GPU Memory (AMD MI325X)8x 256 GB HBM3e per node (2,048 GB total GPU memory)
GPU Interconnect BandwidthUp to 900 GB/s bidirectional per GPU (NVLink 4.0 / Infinity Fabric)
System Memory TypeDDR5 RDIMM / 3DS RDIMM
System Memory Slots24 DIMM slots (12 per processor)
Maximum System MemoryUp to 6 TB DDR5
Storage BaysUp to 12x NVMe SSD (front accessible)
Network Fabric SupportHPE Slingshot 200Gb/s Ethernet / HDR InfiniBand; front-end Ethernet via OCP NIC 3.0 slot
PCIe GenerationPCIe Gen 5.0
Power SupplyRedundant Titanium-level high-efficiency PSUs (N+1 or 2+2 configuration)
Power InputAC 200–240V; DC option available
CoolingHigh-velocity forced-air cooling; direct liquid cooling (DLC) ready
ManagementHPE iLO 6 (Integrated Lights-Out) with hardware root-of-trust, telemetry streaming, and zero-trust security architecture
Operating System SupportRed Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu Server LTS, Rocky Linux
Cluster Software IntegrationHPE Cray Programming Environment, Slurm, PBS Pro, Kubernetes with GPU Operator
Platform Launch2025 Q2
Standards ComplianceASHRAE A2/W35 thermal specifications; IEC, UL, CE safety certifications

Frequently Asked Questions about HPE ProLiant Compute XD685 Server

What does the HPE ProLiant Compute XD685 Server do?

The HPE ProLiant Compute XD685 Server is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE ProLiant Compute XD685 Server?

Key specifications for the HPE ProLiant Compute XD685 Server: new condition; manufacturer HPE; product line HPE ProLiant Compute XD685; form factor 4U Rack Server; processor family AMD EPYC (Genoa/Bergamo generation); processor sockets 2; gpu configuration 8x GPU accelerator slots (full SXM5/OAM form factor). Manufacturer part number P63500-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.