Brand: HPE | Category: Servers
SKU: HP-P75320B21 | Part #: P75320-B21 | MPN: P75320-B21
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The HPE ProLiant Compute XD685 Gen12 is a purpose-built, dense 5U rack-mount server architected specifically for the most demanding generative AI training and large language model workloads at hyperscale. Designed to accommodate eight AMD Instinct MI325X GPU accelerators per node, the system delivers exceptional FP8, BF16, and FP16 compute throughput while maintaining the thermal and power delivery infrastructure required to sustain peak AI training performance continuously. The XD685 Gen12 leverages a next-generation AMD EPYC processor platform to provide the memory bandwidth and PCIe interconnect capacity necessary to feed eight high-performance accelerators without CPU-side bottlenecks, making it a fully balanced training node for transformer-based and diffusion-based model architectures.
The chassis integrates high-bandwidth NVMe storage for dataset staging and checkpoint operations, and supports high-speed GPU-to-GPU fabric connectivity through AMD Infinity Fabric links, enabling tight multi-GPU coupling within the node. The system is designed to operate within dense rack configurations and connects seamlessly into scale-out AI training clusters via 400GbE or InfiniBand HDR/NDR networking, supporting the all-reduce communication patterns that define distributed training at scale. HPE's silicon-to-systems engineering approach ensures that power delivery, cooling, and management firmware are co-optimized for sustained AI compute duty cycles that can run continuously for weeks during large model training runs.
Management is handled through the HPE iLO 7 Baseboard Management Controller, which provides deep telemetry visibility into accelerator utilization, thermal margins, power consumption per rail, and predictive failure analytics across the entire node. The XD685 Gen12 integrates natively into HPE GreenLake for HPC & AI management frameworks, allowing operators to monitor and orchestrate fleets of AI training nodes through a unified control plane. Its dense form factor—delivering eight accelerators per 5U—optimizes rack-level accelerator density, reducing the physical footprint of large GPU clusters without sacrificing per-node performance or serviceability access.
| Manufacturer | HP (Hewlett Packard Enterprise) |
| Product Line | HPE ProLiant Compute XD685 Gen12 |
| Form Factor | 5U Rack-Mount |
| CPU Architecture | AMD EPYC Gen5 (Zen 5) dual-socket |
| Max CPU Cores | Up to 256 total cores (2x 128-core EPYC processors) |
| GPU Accelerators Supported | 8x AMD Instinct MI325X per node |
| GPU Interconnect | AMD Infinity Fabric (XGMI) high-bandwidth GPU-to-GPU fabric |
| Accelerator Memory | Up to 1,536 GB HBM3 total (8x 192 GB per MI325X) |
| System Memory Type | DDR5 ECC Registered DIMMs |
| System Memory Capacity | Up to 6 TB DDR5 across 24 DIMM slots per socket |
| PCIe Generation | PCIe Gen 5.0 x16 per accelerator slot |
| Internal Storage | Up to 8x NVMe U.2/E3.S Gen5 drives for dataset staging and checkpoint storage |
| Network Interface Options | Dual 400GbE OSFP / InfiniBand NDR 400 Gb/s per node (OCP 3.0 NIC slots) |
| Power Supply | Redundant 80 PLUS Titanium PSUs, N+1 hot-plug configuration |
| Max System Power | Up to 10 kW per node (configured with 8x MI325X at TDP) |
| Cooling | High-volume hot-plug fan modules with rear-exhaust airflow optimized for GPU thermal dissipation |
| Management Controller | HPE iLO 7 BMC with Redfish API, IPMI 2.0, integrated GPU telemetry and predictive analytics |
| Management Software Integration | HPE GreenLake for HPC & AI, HPE Cray ClusterStor compatible, Slurm and Kubernetes operator support |
| OS Support | Red Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu Server LTS, ROCm software stack natively supported |
| Security Features | HPE Silicon Root of Trust, Secure Boot, UEFI firmware signed validation, iLO Advanced security controls |
| Rack Units | 5U |
| Launch Generation | Gen12 (2025-Q4) |
Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.
| Brand | HPE |
| Category | Servers |
| SKU | HP-P75320B21 |
| Part Number | P75320-B21 |
| Condition | New |
| Product Line | HPE ProLiant Compute XD685 Gen12 |
| Form Factor | 5U Rack-Mount |
| CPU Architecture | AMD EPYC Gen5 (Zen 5) dual-socket |
| Max CPU Cores | Up to 256 total cores (2x 128-core EPYC processors) |
| GPU Accelerators Supported | 8x AMD Instinct MI325X per node |
| GPU Interconnect | AMD Infinity Fabric (XGMI) high-bandwidth GPU-to-GPU fabric |
| Accelerator Memory | Up to 1,536 GB HBM3 total (8x 192 GB per MI325X) |
| System Memory Type | DDR5 ECC Registered DIMMs |
| System Memory Capacity | Up to 6 TB DDR5 across 24 DIMM slots per socket |
| PCIe Generation | PCIe Gen 5.0 x16 per accelerator slot |
| Internal Storage | Up to 8x NVMe U.2/E3.S Gen5 drives for dataset staging and checkpoint storage |
| Network Interface Options | Dual 400GbE OSFP / InfiniBand NDR 400 Gb/s per node (OCP 3.0 NIC slots) |
| Power Supply | Redundant 80 PLUS Titanium PSUs, N+1 hot-plug configuration |
| Max System Power | Up to 10 kW per node (configured with 8x MI325X at TDP) |
| Cooling | High-volume hot-plug fan modules with rear-exhaust airflow optimized for GPU thermal dissipation |
| Management Controller | HPE iLO 7 BMC with Redfish API, IPMI 2.0, integrated GPU telemetry and predictive analytics |
| Management Software Integration | HPE GreenLake for HPC & AI, HPE Cray ClusterStor compatible, Slurm and Kubernetes operator support |
| OS Support | Red Hat Enterprise Linux, SUSE Linux Enterprise Server, Ubuntu Server LTS, ROCm software stack natively supported |
| Security Features | HPE Silicon Root of Trust, Secure Boot, UEFI firmware signed validation, iLO Advanced security controls |
| Rack Units | 5U |
| Launch Generation | Gen12 (2025-Q4) |
The HPE ProLiant Compute XD685 Gen12 is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.
Key specifications for the HPE ProLiant Compute XD685 Gen12: new condition; manufacturer HP (Hewlett Packard Enterprise); product line HPE ProLiant Compute XD685 Gen12; form factor 5U Rack-Mount; cpu architecture AMD EPYC Gen5 (Zen 5) dual-socket; max cpu cores Up to 256 total cores (2x 128-core EPYC processors); gpu accelerators supported 8x AMD Instinct MI325X per node. Manufacturer part number P75320-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.