HPE P43337-B21 - HPE 256GB DDR5-4800
Brand: HPE | Category: Memory (RAM)
SKU: HPE-P43337-B21 | Part #: P43337-B21 | MPN: P43337-B21
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About the HPE P43337-B21 - HPE 256GB DDR5-4800
HPE ProLiant Gen10 Plus and Gen11 server platforms demand memory that matches their processing power, and the HPE P43337-B21 delivers exactly that. This 256GB DDR5-4800 RDIMM is engineered for mission-critical enterprise workloads where capacity and reliability cannot be compromised. Built to HPE's exacting standards, the P43337-B21 combines high-speed DDR5 technology with robust error correction, making it the choice for infrastructure teams running virtualization, database, and analytics at scale.
The module operates at 4800 MT/s (PC5-38400) with a 42 CAS latency, delivering the performance demanded by latency-sensitive applications. Its 8-Rank configuration and 72-bit width (with ECC) ensure data integrity across demanding multi-socket deployments. With integrated On-Die ECC (ODECC) plus system-level ECC support, redundancy is built in at every layer. The 288-pin DIMM form factor and Low Profile design fit seamlessly into HPE infrastructure, while HPE Smart Memory features optimize compatibility and performance. Operating at just 1.1V within a standard 0°C to 85°C range, this memory balances power efficiency with thermal stability. IT procurement teams and infrastructure architects seeking to maximize per-socket capacity while maintaining enterprise-grade reliability will find the P43337-B21 indispensable.
Deployment Scenarios
- Large-scale virtualization environments requiring 256GB per socket in HPE ProLiant Gen10 Plus and Gen11 servers
- In-memory database and analytics platforms demanding ultra-low latency at 4800 MT/s DDR5 speeds
- High-availability clustered applications where On-Die ECC and system-level ECC protect against silent data corruption
- Multi-socket configurations where 8-Rank modules maximize memory density per server
- Mission-critical workloads in data centres where HPE Smart Memory ensures optimal configuration and performance tuning
For current availability, specifications, and enterprise licensing options on the HPE P43337-B21, contact Omnixon Global to submit your RFQ.
Technical Specifications
| Brand | HPE |
| Category | Memory (RAM) |
| SKU | HPE-P43337-B21 |
| Part Number | P43337-B21 |
| Condition | New |
| Capacity | 256GB |
| Form Factor | DIMM (288-pin) |
| Interface | Registered DIMM (RDIMM/LRDIMM) |
| Speed | 4800 MT/s |
| Manufacturer Part Number | P43337-B21 |
| Module Capacity | 256GB |
| Memory Technology | DDR5 |
| Memory Speed | 4800 MT/s (PC5-38400) |
| Module Type | RDIMM (Registered DIMM) |
| Module Form Factor | 288-pin DIMM |
| ECC Support | Yes — On-Die ECC (ODECC) plus system-level ECC |
| Ranks | 8-Rank (8R) |
| Data Width | 64-bit (72-bit with ECC) |
| Operating Voltage | 1.1V |
| CAS Latency | 42 |
| Compatible Server Families | HPE ProLiant Gen10 Plus, HPE ProLiant Gen11 |
| HPE Smart Memory | Yes |
| Operating Temperature | 0°C to 85°C (standard operational range) |
| Module Height | Low Profile (LP) |
Frequently Asked Questions about HPE P43337-B21 - HPE 256GB DDR5-4800
What does the HPE P43337-B21 - HPE 256GB DDR5-4800 do?
The HPE P43337-B21 - HPE 256GB DDR5-4800 is enterprise DIMM (288-pin) memory designed for ECC-protected workloads — virtualization hosts, database servers, analytics platforms, and AI training rigs. HPE validates this module against major server vendor compatibility matrices.
What are the headline specs of the HPE P43337-B21 - HPE 256GB DDR5-4800?
Key specifications for the HPE P43337-B21 - HPE 256GB DDR5-4800: capacity 256GB; form factor DIMM (288-pin); interface Registered DIMM (RDIMM/LRDIMM); Lifetime support (HPE Smart Memory) support; new condition. Manufacturer part number P43337-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.
Is the HPE P43337-B21 - HPE 256GB DDR5-4800 compatible with my infrastructure?
The HPE P43337-B21 - HPE 256GB DDR5-4800 fits DIMM (288-pin) memory slots and is compatible with major server platforms validated by HPE. Server vendor IPL/HCL compatibility (Dell PowerEdge, HPE ProLiant, Lenovo ThinkSystem, Supermicro) is checked at quote time so you don't risk a memory-channel mismatch.