Brand: HPE | Category: Enterprise SSDs
SKU: HPE-P40546-B21 | Part #: P40546-B21 | MPN: P40546-B21
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The HPE P40546-B21 delivers exceptional power efficiency and performance density for enterprise all-flash storage environments, making it an ideal choice for storage architects and IT infrastructure teams seeking reliable mixed-use workload support. This 3.84TB SSD combines HPE's enterprise-grade reliability with Intel S4610 series technology, providing organizations with a proven storage solution that balances performance, endurance, and operational efficiency across diverse data center applications.
Built on 3D TLC NAND architecture, the P40546-B21 offers sequential read speeds up to 560 MB/s and sequential write speeds up to 510 MB/s, coupled with random read performance reaching 97,000 IOPS and random write performance at 36,000 IOPS at 4K block size. The drive is engineered with power-loss data protection and end-to-end data path protection to safeguard critical business data, while hot-plug support enables seamless maintenance without downtime. HPE has certified this drive for compatibility across ProLiant Gen9 and Gen10 servers, Apollo systems, and Synergy platforms, ensuring broad deployment flexibility. Rated for mixed-use workloads with endurance up to 3 DWPD, the P40546-B21 (part number P40546-B21) is designed to handle sustained enterprise operations while maintaining thermal stability across the 0°C to 70°C operating temperature range. The SFF 2.5-inch form factor with basic carrier configuration optimizes rack density, allowing organizations to maximize storage capacity within existing infrastructure footprints.
For detailed specifications, compatibility verification, or volume pricing on the HPE P40546-B21, contact the Omnixon Global team to submit your RFQ today.
| Brand | HPE |
| Category | Enterprise SSDs |
| SKU | HPE-P40546-B21 |
| Part Number | P40546-B21 |
| Condition | New |
| Capacity | 3.84TB |
| Form Factor | 2.5" |
| Interface | SATA 6Gb/s |
| Manufacturer Part Number | P40546-B21 |
| Drive Series | Intel S4610 |
| Raw Capacity | 3.84 TB |
| Interface | SATA 6Gb/s |
| Form Factor | SFF 2.5-inch |
| Carrier Type | Basic Carrier (BC) |
| Drive Type | Solid State Drive (SSD) |
| Workload Classification | Mixed Use |
| NAND Type | 3D TLC NAND |
| Endurance Rating | Mixed Use (up to 3 DWPD — per Intel S4610 series specification) |
| Sequential Read Speed | Up to 560 MB/s |
| Sequential Write Speed | Up to 510 MB/s |
| Random Read IOPS (4K) | Up to 97,000 IOPS |
| Random Write IOPS (4K) | Up to 36,000 IOPS |
| Power-Loss Data Protection | Yes |
| End-to-End Data Path Protection | Yes |
| Hot-Plug Support | Yes |
| Compatible Server Platforms | HPE ProLiant Gen9, Gen10; HPE Apollo; HPE Synergy |
| Operating Temperature | 0°C to 70°C |
| HPE QuickSpecs Validated | Yes |
At 3.84TB, the HPE P40546-B21 - HPE 3.84TB SATA 6G Mixed Use SFF BC S4610 SSD suits enterprise data-center storage tiers — all-flash arrays, hyperconverged storage pools (vSAN, Ceph), database backends, and high-throughput backup repositories. The SATA 6G interface is supported by major server platforms.
Key specifications for the HPE P40546-B21 - HPE 3.84TB SATA 6G Mixed Use SFF BC S4610 SSD: capacity 3.84TB; form factor SFF (2.5in); interface SATA 6G; 3 to 5 years (HPE manufacturer) support; new condition. Manufacturer part number P40546-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.
The HPE P40546-B21 - HPE 3.84TB SATA 6G Mixed Use SFF BC S4610 SSD uses a SATA 6G interface in a SFF (2.5in) form factor. It's compatible with server platforms that expose this interface — typical deployments include Dell PowerEdge, HPE ProLiant, Lenovo ThinkSystem, and Supermicro SuperServer chassis. For specific vendor part-number compatibility, our team validates against the manufacturer support matrix.