HPE AMD Radeon Pro W7900 48GB GDDR6 PCIe Workstation GPU

HPE AMD Radeon Pro W7900 48GB GDDR6 PCIe Workstation GPU

Brand: HPE | Category: GPUs

SKU: P53869-B21 | Part #: P53869-B21 | MPN: P53869-B21

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About the HPE AMD Radeon Pro W7900 48GB GDDR6 PCIe Workstation GPU

The HPE AMD Radeon Pro W7900 48GB GDDR6 PCIe Workstation GPU (P53869-B21) is built on AMD's RDNA 3 architecture, delivering a substantial leap in compute throughput, memory bandwidth, and graphics fidelity for professional workstation environments. With 48GB of GDDR6 memory across a 384-bit memory interface, this GPU provides the capacity to handle extremely large datasets, complex scene geometry, and high-resolution rendering tasks without memory bottlenecks that would otherwise force data paging.

Designed for the demands of modern enterprise workstations, the W7900 supports PCIe 4.0 x16 connectivity and includes DisplayPort 2.1 outputs capable of driving ultra-high-resolution multi-display configurations. The card leverages AMD's RDNA 3 compute units and hardware-accelerated ray tracing to accelerate professional visualization pipelines, including real-time rendering in AEC, media and entertainment, and product design workflows. AMD's ROCm open software ecosystem enables GPU compute acceleration for HPC and AI inferencing tasks alongside traditional graphics workloads.

As an HPE-branded and validated component (part number P53869-B21), this GPU is qualified for integration into HPE Z-class workstation platforms and HPE's broader enterprise procurement and lifecycle management frameworks. It is ISV-certified for leading professional applications across engineering simulation, content creation, and scientific visualization, making it a reliable choice for enterprise IT teams standardizing on validated, high-performance graphics hardware.

Ideal for

  • High-end 3D CAD and BIM visualization for AEC and manufacturing engineering teams requiring large in-memory scene handling
  • Real-time ray-traced rendering and virtual production workflows in media, broadcast, and entertainment studios
  • AI inferencing and GPU-accelerated compute workloads using the AMD ROCm open software platform in research and HPC environments
  • Multi-display professional visualization setups for command-and-control, simulation, and data analytics operations centers
  • Medical imaging and scientific visualization applications demanding high memory capacity and ISV-certified GPU stability
  • Digital twin development and immersive XR content creation requiring sustained high-throughput graphics compute performance

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP53869-B21
GPU ModelAMD Radeon Pro W7900
ArchitectureAMD RDNA 3
Memory Capacity48GB GDDR6
Memory Interface384-bit
Memory Bandwidth864 GB/s
PCIe InterfacePCIe 4.0 x16
Compute Units96
Peak Single-Precision Performance61.3 TFLOPS
Display Outputs3x DisplayPort 2.1, 1x Mini DisplayPort 2.1
Max Displays Supported6 (with DisplayPort MST)
Max Display ResolutionUp to 8K
Power Connectors2x 8-pin
Thermal Design Power (TDP)295W
Form FactorDual-slot, full-height
API SupportDirectX 12 Ultimate, Vulkan, OpenGL 4.6, OpenCL 2.0, ROCm
ISV CertificationsCertified for major professional applications including Autodesk, Dassault Systèmes, and Siemens
Hardware Ray TracingYes (2nd generation AMD Ray Accelerators)
ECC Memory SupportYes

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryGPUs
SKUP53869-B21
Part NumberP53869-B21
ConditionNew
Manufacturer Part NumberP53869-B21
GPU ModelAMD Radeon Pro W7900
ArchitectureAMD RDNA 3
Memory Capacity48GB GDDR6
Memory Interface384-bit
Memory Bandwidth864 GB/s
PCIe InterfacePCIe 4.0 x16
Compute Units96
Peak Single-Precision Performance61.3 TFLOPS
Display Outputs3x DisplayPort 2.1, 1x Mini DisplayPort 2.1
Max Displays Supported6 (with DisplayPort MST)
Max Display ResolutionUp to 8K
Power Connectors2x 8-pin
Thermal Design Power (TDP)295W
Form FactorDual-slot, full-height
API SupportDirectX 12 Ultimate, Vulkan, OpenGL 4.6, OpenCL 2.0, ROCm
ISV CertificationsCertified for major professional applications including Autodesk, Dassault Systèmes, and Siemens
Hardware Ray TracingYes (2nd generation AMD Ray Accelerators)
ECC Memory SupportYes

Frequently Asked Questions about HPE AMD Radeon Pro W7900 48GB GDDR6 PCIe Workstation GPU

What server platforms accept the HPE AMD Radeon Pro W7900 48GB GDDR6 PCIe Workstation GPU?

Reference servers include Dell PowerEdge XE9680 / XE9712, HPE Cray XD670, Lenovo ThinkSystem SR685a / SR675 V3, Supermicro AS-A21GE / SYS-821GE, Gigabyte G593 / G894, ASUS ESC. Share your target platform in the RFQ and we will confirm chassis-to-GPU compatibility and recommended NIC pairing.

How long is the lead time on AI GPUs?

Highly model-dependent. L40S / RTX-class: typically 3-6 weeks. H100/H200/B200 in SXM form factor: 12-16 weeks for whole-platform allocations. We quote genuine-channel ETAs only — no grey-market promises.

Do you supply matched networking (Quantum InfiniBand / Spectrum-X)?

Yes — Omnixon stocks the full NVIDIA networking lineup (Quantum-2 / Quantum-X InfiniBand, Spectrum-X Ethernet, ConnectX NICs, BlueField DPUs) so we can quote a complete training-cluster BOM, not just the GPUs.

Can you help with NVIDIA AI Enterprise licensing?

Yes. We hold genuine-channels for NVIDIA AI Enterprise software subscriptions. Add it to your RFQ and we quote node-aligned licensing along with the hardware.