HPE AMD Instinct MI250X 128GB OAM GPU Accelerator

Brand: HPE | Category: GPUs

SKU: P48851-B21 | Part #: P48851-B21 | MPN: P48851-B21

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The HPE AMD Instinct MI250X 128GB OAM GPU Accelerator (P48851-B21) is an OCP Accelerator Module v1.0 form factor GPU equipped with direct liquid cooling, engineered for high-performance compute and AI workloads requiring extreme throughput and precision flexibility. Built on AMD's CDNA2 architecture, this accelerator pairs a dual graphics compute die configuration via AMD Infinity Fabric to deliver 220 total compute units—110 per GCD. The 128 GB HBM2e memory subsystem achieves 3.2 TB/s aggregate bandwidth, ensuring data-hungry algorithms maintain steady compute utilization. Peak performance spans FP64 at 47.9 TFLOPS, FP64 Matrix Core operations at 95.7 TFLOPS, and mixed-precision workloads up to 383.0 TFLOPS in both FP16 and BF16 formats. Support for FP64, FP32, FP16, BF16, INT8, and INT4 precision modes grants flexibility across scientific simulation, deep learning training, and inference pipelines. The 500W thermal design power is managed by direct liquid cooling, while AMD Infinity Fabric enables seamless multi-GPU peer-to-peer communication. PCIe Gen4 x16 connectivity via the OAM baseboard provides host interface capability.

HPE's MI250X accelerator targets artificial intelligence infrastructure teams, HPC centers, and hyperscale research organizations deploying large-scale model training and scientific computing clusters. These buyers prioritize memory capacity and bandwidth density to minimize training iteration time and reduce total cost of ownership in mixed-precision environments. The modular OAM design integrates directly into OCP-compliant systems, simplifying deployment and reducing integration risk in standardized data center architectures.

The AMD ROCm software stack—supporting PyTorch, TensorFlow, JAX, and OpenMPI—ensures compatibility with mainstream frameworks and distributed training protocols. For pricing, availability, and system integration support for the HPE AMD Instinct MI250X with part number P48851-B21, contact Omnixon Global to submit your request for quotation.