HPE 64GB (1x64GB) Quad Rank x4 DDR4-2400 CAS-17-17-17 Load Reduced Smart Memory Kit

HPE 64GB (1x64GB) Quad Rank x4 DDR4-2400 CAS-17-17-17 Load Reduced Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: 805353-B21 | Part #: 805353-B21 | MPN: 805353-B21

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About the HPE 64GB (1x64GB) Quad Rank x4 DDR4-2400 CAS-17-17-17 Load Reduced Smart Memory Kit

The HPE 64GB (1x64GB) Quad Rank x4 DDR4-2400 CAS-17-17-17 Load Reduced Smart Memory Kit (805353-B21) is a high-capacity LRDIMM engineered for HPE Gen9 and select Gen10 ProLiant and Synergy server platforms. Built on DDR4-2400 MHz architecture with a CAS latency of 17-17-17, this module delivers a balance of high memory bandwidth and improved electrical loading characteristics through its load-reduced design, enabling servers to support greater memory capacity per channel than standard registered DIMMs allow. The x4 DRAM width and Quad Rank configuration maximize per-slot density, making this kit the appropriate choice when maximum memory population and aggregate system capacity take priority.

As an HPE Smart Memory component, the module incorporates an on-DIMM serial presence detect (SPD) mechanism that communicates directly with HPE's Advanced Memory Protection (AMP) technologies embedded in the server platform. This integration unlocks HPE-specific reliability, availability, and serviceability (RAS) features including online spare memory, mirrored memory configurations, and Advanced ECC, all of which are unavailable to non-HPE-qualified DIMMs in these platforms. The load-reduced buffer isolates the DRAM from the memory bus, reducing signal load and supporting higher DIMM counts per channel at maintained frequencies.

This module is purpose-built for memory-intensive enterprise datacenter workloads where aggregate capacity per server is a primary constraint. Environments running large in-memory databases, scale-up virtualization hosts, SAP HANA appliances, and high-throughput analytics platforms benefit directly from the density this 64GB LRDIMM provides. The module operates at 1.2V, aligning with DDR4 power efficiency standards, and is manufactured and tested to HPE's component qualification standards to ensure compatibility and stability across supported server generations.

Ideal for

  • Scale-up virtualization hosts (VMware vSphere, Microsoft Hyper-V) requiring maximum VM density per physical server node
  • In-memory database deployments such as SAP HANA, Oracle In-Memory, and Microsoft SQL Server In-Memory OLTP where working dataset must reside entirely in RAM
  • High-performance analytics and business intelligence platforms processing large datasets without repeated storage I/O
  • AI and machine learning inference servers where large model parameters and feature sets must be held in system memory during processing
  • Enterprise private cloud infrastructure nodes where memory overcommit ratios and tenant isolation demands require high aggregate capacity
  • Mission-critical ERP and transactional application servers where HPE Advanced Memory Protection mirroring or online spare configurations are required for RAS compliance

Technical specifications

ManufacturerHPE
Manufacturer Part Number805353-B21
Module Capacity64GB
Kit Configuration1 x 64GB
Memory TypeDDR4
Module Form FactorLRDIMM (Load Reduced DIMM)
SpeedDDR4-2400 (PC4-2400T-L)
CAS LatencyCAS 17-17-17
RankQuad Rank (4Rx4)
DRAM Widthx4
Operating Voltage1.2V
Error CorrectionECC (Error Correcting Code)
Pin Count288-pin
Register TypeLoad Reduced (LRDIMM buffer)
HPE Smart MemoryYes
Compatible Server FamiliesHPE ProLiant Gen9 (e.g. DL580 Gen9, DL360 Gen9, DL380 Gen9), select HPE Synergy compute modules
HPE AMP SupportOnline Spare, Mirrored Memory, Advanced ECC (platform-dependent)
RoHS CompliantYes

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryMemory (RAM)
SKU805353-B21
Part Number805353-B21
ConditionNew
Manufacturer Part Number805353-B21
Module Capacity64GB
Kit Configuration1 x 64GB
Memory TypeDDR4
Module Form FactorLRDIMM (Load Reduced DIMM)
SpeedDDR4-2400 (PC4-2400T-L)
CAS LatencyCAS 17-17-17
RankQuad Rank (4Rx4)
DRAM Widthx4
Operating Voltage1.2V
Error CorrectionECC (Error Correcting Code)
Pin Count288-pin
Register TypeLoad Reduced (LRDIMM buffer)
HPE Smart MemoryYes
Compatible Server FamiliesHPE ProLiant Gen9 (e.g. DL580 Gen9, DL360 Gen9, DL380 Gen9), select HPE Synergy compute modules
HPE AMP SupportOnline Spare, Mirrored Memory, Advanced ECC (platform-dependent)
RoHS CompliantYes

Frequently Asked Questions about HPE 64GB (1x64GB) Quad Rank x4 DDR4-2400 CAS-17-17-17 Load Reduced Smart Memory Kit

Is the HPE 64GB (1x64GB) Quad Rank x4 DDR4-2400 CAS-17-17-17 Load Reduced Smart Memory Kit compatible with my server?

Part number 805353-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.

What support applies to this memory module?

Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.

How do I request a quote?

Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.