HPE 48GB (1x48GB) DDR5-5600 CAS-46 Dual Rank x8 Registered Smart Memory Kit

HPE 48GB (1x48GB) DDR5-5600 CAS-46 Dual Rank x8 Registered Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: P64348-B21 | Part #: P64348-B21 | MPN: P64348-B21

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About the HPE 48GB (1x48GB) DDR5-5600 CAS-46 Dual Rank x8 Registered Smart Memory Kit

The HPE 48GB (1x48GB) DDR5-5600 CAS-46 Dual Rank x8 Registered Smart Memory Kit (P64348-B21) represents HPE's latest generation of enterprise-class server memory, built on the DDR5 architecture to deliver substantially higher bandwidth, improved power efficiency, and greater capacity scalability compared to previous DDR4 generations. Operating at a validated speed of 5600 MT/s with a CAS latency of 46, this module is engineered to meet the rigorous demands of modern enterprise infrastructure, providing the throughput required by memory-intensive applications across compute-dense server environments.

As a Registered DIMM (RDIMM), this kit incorporates an onboard register that buffers command and address signals between the memory controller and DRAM devices, enabling greater electrical stability and supporting higher memory capacities per server than unbuffered alternatives. The dual rank x8 configuration balances capacity and signal integrity, making it well-suited for multi-DIMM-per-channel deployments in HPE ProLiant Gen11 servers. HPE Smart Memory technology embeds an onboard SPD (Serial Presence Detect) that is authenticated by the server's BIOS, enabling automatic speed and timing optimization and allowing HPE iLO to report detailed memory health and diagnostic data.

With a 48GB capacity per module, this kit addresses the growing memory footprint requirements of AI inference, large in-memory databases, virtualization hosts, and high-performance analytics platforms. The DDR5 standard's native support for on-die ECC (error correction within the DRAM die itself), combined with HPE's validated testing and server-level ECC, provides multiple layers of data integrity protection suited to mission-critical enterprise and datacenter deployments across UAE, GCC, EMEA, and APAC regions.

Ideal for

  • High-density VMware vSphere or Microsoft Hyper-V virtualization hosts requiring large aggregate memory pools across multiple virtual machines
  • In-memory database platforms such as SAP HANA, Redis, or Oracle In-Memory where dataset size directly constrains query throughput and latency
  • AI and machine learning inference servers where large model weights and activation data must reside in fast, low-latency system memory
  • High-performance computing (HPC) workloads involving large-scale numerical simulations, genomics, or computational fluid dynamics requiring high memory bandwidth
  • Enterprise data analytics and business intelligence platforms processing large datasets entirely in-memory for sub-second query response times
  • Cloud-native and containerized workloads on HPE ProLiant Gen11 infrastructure where per-node memory capacity directly enables higher pod and container density

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP64348-B21
Module Capacity48GB
Kit Configuration1x48GB
Memory TechnologyDDR5
Memory Speed5600 MT/s
CAS Latency46 (CL46)
Module TypeRDIMM (Registered DIMM)
Rank ConfigurationDual Rank
DRAM Device Widthx8
Error CorrectionECC (with on-die ECC)
Form Factor288-pin DIMM
HPE Smart MemoryYes
Compatible Server GenerationHPE ProLiant Gen11
Operating Voltage1.1V
RoHS CompliantYes

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryMemory (RAM)
SKUP64348-B21
Part NumberP64348-B21
ConditionNew
Manufacturer Part NumberP64348-B21
Module Capacity48GB
Kit Configuration1x48GB
Memory TechnologyDDR5
Memory Speed5600 MT/s
CAS Latency46 (CL46)
Module TypeRDIMM (Registered DIMM)
Rank ConfigurationDual Rank
DRAM Device Widthx8
Error CorrectionECC (with on-die ECC)
Form Factor288-pin DIMM
HPE Smart MemoryYes
Compatible Server GenerationHPE ProLiant Gen11
Operating Voltage1.1V
RoHS CompliantYes

Frequently Asked Questions about HPE 48GB (1x48GB) DDR5-5600 CAS-46 Dual Rank x8 Registered Smart Memory Kit

Is the HPE 48GB (1x48GB) DDR5-5600 CAS-46 Dual Rank x8 Registered Smart Memory Kit compatible with my server?

Part number P64348-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.

What support applies to this memory module?

Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.

How do I request a quote?

Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.