HPE 256GB 4Rx4 PC5-5600AA-R RDIMM Smart Memory Gen11
Brand: HPE | Category: Memory (RAM)
SKU: P64338-B21 | Part #: P64338-B21 | MPN: P64338-B21
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About the HPE 256GB 4Rx4 PC5-5600AA-R RDIMM Smart Memory Gen11
DDR5 at 5600 MT/s with 256 GB capacity, the HPE 256GB 4Rx4 PC5-5600AA-R RDIMM Smart Memory Gen11 (part number P64338-B21) delivers enterprise-grade memory performance and reliability for mission-critical infrastructure. Built as a Registered Dual In-Line Memory Module with quad-rank (4Rx4) organization and 288-pin form factor, this module is purpose-engineered for HPE ProLiant Gen11 servers and validated across HPE Smart Memory platform capabilities. The module operates at 1.1 V within a standard thermal envelope of 0°C to 85°C, ensuring stable performance under demanding workloads.
Data integrity is central to this design. The DDR5 on-die ECC combined with system-level ECC and registered buffer technology provides advanced error correction, protecting against single-bit and multi-bit failures that can compromise uptime. Full RoHS compliance underscores HPE's commitment to sustainable, regulated manufacturing. For IT procurement teams evaluating memory upgrades to HPE ProLiant Gen11 infrastructure, this 256 GB module achieves the balance of capacity, speed, and reliability required in large-scale deployments. The PC5-5600AA-R speed grade enables high throughput at 5600 MT/s, supporting bandwidth-intensive applications without thermal compromise.
Enterprise Deployment Scenarios
- Virtualization and consolidated workloads requiring high memory density and fail-safe ECC protection across HPE ProLiant Gen11 platforms
- Database and in-memory analytics where 256 GB per module accelerates query performance and reduces module count per server
- High-performance computing clusters benefiting from DDR5 speed grade (PC5-5600AA-R) and registered memory stability
- Mission-critical transactional systems where on-die ECC and advanced error correction minimize unplanned downtime
- Multi-socket Gen11 deployments scaling memory capacity while maintaining thermal and power efficiency at 1.1 V
To request detailed specifications, compatibility matrices, or volume pricing for the HPE P64338-B21 module, contact Omnixon Global today.
Technical Specifications
| Brand | HPE |
| Category | Memory (RAM) |
| SKU | P64338-B21 |
| Part Number | P64338-B21 |
| Condition | New |
| Manufacturer Part Number | P64338-B21 |
| Module Type | RDIMM (Registered Dual In-Line Memory Module) |
| Capacity | 256 GB |
| DDR Generation | DDR5 |
| Speed Grade | PC5-5600AA-R |
| Data Transfer Rate | 5600 MT/s |
| Rank Configuration | 4Rx4 (Quad Rank, ×4 DRAM organization) |
| ECC Support | Yes — DDR5 on-die ECC plus system-level ECC |
| Form Factor | 288-pin DIMM |
| Voltage | 1.1V |
| HPE Smart Memory | Yes — validated for HPE ProLiant Gen11 platform features |
| Compatible Server Generation | HPE ProLiant Gen11 |
| Error Correction | Advanced ECC with on-die ECC (DDR5 native) and registered buffer for signal integrity |
| Operating Temperature | 0°C to 85°C (standard RDIMM thermal envelope) |
| RoHS Compliance | Yes |
Frequently Asked Questions about HPE 256GB 4Rx4 PC5-5600AA-R RDIMM Smart Memory Gen11
Is the HPE 256GB 4Rx4 PC5-5600AA-R RDIMM Smart Memory Gen11 compatible with my server?
Part number P64338-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.
What support applies to this memory module?
Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.
How do I request a quote?
Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.