HPE 16GB 2Rx8 PC4-2666V-R RDIMM SmartMemory

HPE 16GB 2Rx8 PC4-2666V-R RDIMM SmartMemory

Brand: HPE | Category: Memory (RAM)

SKU: 838081-B21 | Part #: 838081-B21 | MPN: 838081-B21

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About the HPE 16GB 2Rx8 PC4-2666V-R RDIMM SmartMemory

The HPE 16GB 2Rx8 PC4-2666V-R RDIMM SmartMemory (838081-B21) is a registered DDR4 dual-rank memory module engineered to HPE's exacting specifications for Gen10 and select Gen9 ProLiant server platforms. Operating at a native clock speed of 2666 MT/s with a 1.2V operating voltage, this module delivers a balance of high-bandwidth throughput and energy efficiency suited to the demands of modern datacenter infrastructure. The dual-rank, x8 organization across a 288-pin RDIMM form factor provides broad slot compatibility and predictable performance across HPE's validated hardware ecosystem.

As HPE SmartMemory, this module carries an embedded SPD that is recognized and authenticated by HPE ProLiant server firmware at POST. This authentication unlocks full feature access — including HPE Advanced Memory Protection technologies such as Advanced ECC and online spare memory — which remain unavailable or degraded when non-HPE memory is installed. The on-module SPD data also enables HPE Insight Diagnostics and iLO health monitoring to report accurate module health, operating conditions, and predictive failure analytics, supporting proactive maintenance strategies in enterprise environments.

This RDIMM is suited to mixed general-purpose and data-intensive server workloads where registered buffering is required to maintain signal integrity across densely populated memory configurations. Typical deployment scenarios include multi-socket ProLiant DL380 Gen10, DL360 Gen10, and ML350 Gen10 platforms running virtualization, database, ERP, and analytics workloads. For organizations operating datacenter fleets across UAE, GCC, EMEA, and APAC regions, Omnixon Global provides access to HPE SmartMemory inventory to support both new deployments and incremental capacity expansions.

Ideal for

  • Expanding memory capacity in HPE ProLiant Gen10 servers running VMware vSphere or Microsoft Hyper-V virtualization to increase virtual machine density per host
  • Scaling in-memory database performance on platforms running SAP HANA, Oracle Database, or Microsoft SQL Server where large working-set data must reside in RAM
  • Supporting AI inference and analytics workloads on HPE Apollo and ProLiant platforms where high memory bandwidth across multiple populated channels is required
  • Replacing or augmenting memory in enterprise ERP environments such as SAP S/4HANA deployments that demand validated, firmware-authenticated HPE SmartMemory for full RAS feature support
  • Populating HPE ProLiant DL360 Gen10 or DL380 Gen10 nodes in hyperconverged infrastructure clusters where uniform, HPE-validated memory is required for consistent performance and supportability
  • Deploying high-availability configurations using HPE Advanced Memory Protection features — including online spare and mirrored memory modes — in mission-critical financial or healthcare IT environments

Technical specifications

ManufacturerHPE
Manufacturer Part Number838081-B21
Memory Capacity16 GB
Memory TechnologyDDR4
Module TypeRDIMM (Registered DIMM)
Form Factor288-pin DIMM
Speed2666 MT/s (PC4-2666V-R)
Rank Configuration2Rx8 (Dual Rank, x8 organization)
Error CorrectionECC (Error Correcting Code)
Operating Voltage1.2 V
CAS LatencyCL19
Memory SeriesHPE SmartMemory
Compatible Server FamiliesHPE ProLiant Gen10; select HPE ProLiant Gen9
SmartMemory AuthenticationEmbedded SPD recognized by HPE ProLiant firmware at POST for full RAS feature unlock
HPE Advanced Memory Protection SupportYes — supports Advanced ECC, online spare, and mirrored memory modes (platform dependent)
iLO Health Monitoring IntegrationYes — module health, temperature, and predictive failure data surfaced via HPE iLO
RoHS ComplianceYes

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryMemory (RAM)
SKU838081-B21
Part Number838081-B21
ConditionNew
Manufacturer Part Number838081-B21
Memory Capacity16 GB
Memory TechnologyDDR4
Module TypeRDIMM (Registered DIMM)
Form Factor288-pin DIMM
Speed2666 MT/s (PC4-2666V-R)
Rank Configuration2Rx8 (Dual Rank, x8 organization)
Error CorrectionECC (Error Correcting Code)
Operating Voltage1.2 V
CAS LatencyCL19
Memory SeriesHPE SmartMemory
Compatible Server FamiliesHPE ProLiant Gen10; select HPE ProLiant Gen9
SmartMemory AuthenticationEmbedded SPD recognized by HPE ProLiant firmware at POST for full RAS feature unlock
HPE Advanced Memory Protection SupportYes — supports Advanced ECC, online spare, and mirrored memory modes (platform dependent)
iLO Health Monitoring IntegrationYes — module health, temperature, and predictive failure data surfaced via HPE iLO
RoHS ComplianceYes

Frequently Asked Questions about HPE 16GB 2Rx8 PC4-2666V-R RDIMM SmartMemory

Is the HPE 16GB 2Rx8 PC4-2666V-R RDIMM SmartMemory compatible with my server?

Part number 838081-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.

What support applies to this memory module?

Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.

How do I request a quote?

Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.