HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Registered Smart Memory Kit

HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Registered Smart Memory Kit

Brand: HPE | Category: Memory (RAM)

SKU: P43326-B21 | Part #: P43326-B21 | MPN: P43326-B21

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About the HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Registered Smart Memory Kit

The HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Registered Smart Memory Kit (P43326-B21) delivers the next generation of server memory technology for HPE ProLiant Gen11 platforms. Built on the DDR5 architecture, this module operates at 4800 MT/s with a CAS latency profile of 40-39-39, providing a substantial bandwidth improvement over previous DDR4 generations. The single-rank x8 organization optimizes memory channel efficiency for workloads that benefit from lower rank-switching overhead, making it well suited for environments where latency consistency and throughput predictability are critical.

As a Registered (RDIMM) module, this kit incorporates an on-module register that buffers command and address signals between the memory controller and the DRAM components, improving signal integrity and enabling greater memory capacity scalability within supported server configurations. HPE Smart Memory technology embeds an on-module serial presence detect (SPD) mechanism that allows HPE ProLiant and Synergy servers to identify the module, validate compatibility, and unlock platform-specific performance and reliability features that are unavailable with third-party memory. This tight hardware-firmware integration supports HPE's Advanced Memory Protection capabilities on eligible platforms.

Designed and validated for enterprise datacenter, high-performance computing, and AI inference infrastructure, this memory kit meets the demands of memory-intensive virtualization stacks, in-memory databases, and scale-out cloud-native architectures. HPE factory testing and qualification ensure the module meets rigorous reliability and compatibility standards for continuous operation in production server environments, reducing unplanned downtime risk in mission-critical deployments across datacenter, edge, and hybrid cloud infrastructure.

Ideal for

  • Expanding memory capacity in HPE ProLiant Gen11 servers running VMware vSphere or Microsoft Hyper-V virtualization platforms where higher VM density is required
  • Supporting in-memory database workloads such as SAP HANA, Redis, or Microsoft SQL Server In-Memory OLTP that require high memory bandwidth and low-latency access
  • Deploying AI inference nodes and machine learning preprocessing pipelines that benefit from DDR5's increased bandwidth over DDR4 platforms
  • Scaling out enterprise Kubernetes and container orchestration clusters where per-node memory capacity directly affects pod scheduling density
  • Populating HPE ProLiant DL or ML Gen11 servers in high-availability ERP and business-critical application environments demanding validated, server-matched memory
  • Refreshing or expanding memory in HPE Synergy composable infrastructure frames to meet growing workload memory requirements without platform replacement

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP43326-B21
Module Capacity16GB
Kit Configuration1x16GB
Memory TechnologyDDR5
Memory Speed4800 MT/s
CAS LatencyCAS-40-39-39
Module TypeRDIMM (Registered DIMM)
Rank ConfigurationSingle Rank
DRAM Organizationx8
Form Factor288-pin DIMM
Voltage1.1V
Error CorrectionECC (Error Correcting Code)
HPE Smart MemoryYes
Compatible Platform GenerationHPE ProLiant Gen11
Operating Temperature0°C to 85°C
RoHS CompliantYes

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryMemory (RAM)
SKUP43326-B21
Part NumberP43326-B21
ConditionNew
Manufacturer Part NumberP43326-B21
Module Capacity16GB
Kit Configuration1x16GB
Memory TechnologyDDR5
Memory Speed4800 MT/s
CAS LatencyCAS-40-39-39
Module TypeRDIMM (Registered DIMM)
Rank ConfigurationSingle Rank
DRAM Organizationx8
Form Factor288-pin DIMM
Voltage1.1V
Error CorrectionECC (Error Correcting Code)
HPE Smart MemoryYes
Compatible Platform GenerationHPE ProLiant Gen11
Operating Temperature0°C to 85°C
RoHS CompliantYes

Frequently Asked Questions about HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Registered Smart Memory Kit

Is the HPE 16GB (1x16GB) Single Rank x8 DDR5-4800 CAS-40-39-39 Registered Smart Memory Kit compatible with my server?

Part number P43326-B21 is qualified for HPE servers that list compatible memory in their QVL. We verify QVL match before quoting — share your server model in the RFQ and our pre-sales engineers confirm fit, recommended population pattern, and total capacity supported.

What support applies to this memory module?

Full manufacturer support (typically 3 years, RDIMM/LRDIMM SKUs often lifetime against manufacturing defects). All product is sourced through distribution so support registers cleanly under your company name.

How do I request a quote?

Submit the RFQ form on this page with your quantity and destination country. Our pre-sales team responds with a vendor-confirmed quote, availability, and matching server-QVL confirmation if needed.