ASUS ESC4000H-E12 4-GPU Server

ASUS ESC4000H-E12 4-GPU Server

Brand: ASUS | Category: GPUs

SKU: ESC4000H-E12 | Part #: ESC4000H-E12 | MPN: ESC4000H-E12

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About the ASUS ESC4000H-E12 4-GPU Server

The ASUS ESC4000H-E12 is a high-density 4U GPU server engineered for demanding enterprise AI, deep learning, and high-performance computing workloads. Built on the Intel Xeon Scalable (Sapphire Rapids) platform with the Intel C741 chipset, it supports dual processors and delivers the memory bandwidth and PCIe 5.0 connectivity required to feed multiple full-length, double-width GPU accelerators simultaneously. The system accommodates up to four double-slot GPUs in dedicated PCIe 5.0 x16 slots, enabling parallel compute deployments across training, inference, and simulation pipelines without I/O bottlenecks.

Memory scalability is a defining characteristic of the ESC4000H-E12, with support for up to 32 DDR5 DIMM slots across dual processors, accommodating large in-memory datasets essential to large language model (LLM) training and scientific computing. The platform integrates dual 10GbE LAN ports natively, with an OCP 3.0 mezzanine slot for flexible high-speed network expansion including 25GbE, 100GbE, or InfiniBand fabric options. Dual redundant power supply units ensure continuous availability in production datacenter environments.

Designed to ASUS enterprise-grade standards, the ESC4000H-E12 includes out-of-band management via ASUS ASMB11-iKVM baseboard management controller (BMC), enabling remote monitoring, power control, and BIOS management compliant with IPMI 2.0 and Redfish standards. Its tool-less GPU bracket design and front-accessible storage bays reduce maintenance overhead in rack-dense installations. The server is well-suited for deployment in UAE, GCC, EMEA, and APAC datacenters requiring certified enterprise GPU compute infrastructure.

Ideal for

  • Large-scale deep learning model training using frameworks such as TensorFlow and PyTorch across multiple GPU accelerators
  • Enterprise AI inference serving for natural language processing, computer vision, and recommendation engine workloads
  • High-performance computing (HPC) simulations in fields including computational fluid dynamics, financial modeling, and genomics
  • Rendering and visualization pipelines for media production, digital twins, and 3D engineering design environments
  • Data analytics acceleration leveraging GPU-accelerated databases and in-memory compute frameworks at scale
  • Virtual desktop infrastructure (VDI) and GPU-accelerated remote workstation deployments across distributed enterprise campuses

Technical specifications

ManufacturerASUS
Manufacturer Part NumberESC4000H-E12
Form Factor4U Rackmount
CPU SupportDual Intel Xeon Scalable 4th Generation (Sapphire Rapids) processors
ChipsetIntel C741
CPU Sockets2 x LGA4677
Memory Slots32 x DIMM slots (16 per CPU)
Memory TypeDDR5 ECC Registered (RDIMM / 3DS RDIMM)
Max Memory Capacity4TB (with 3DS RDIMMs)
GPU Slots4 x PCIe 5.0 x16 full-length, double-width GPU slots
PCIe Expansion1 x OCP 3.0 mezzanine slot
Storage Bays8 x 2.5-inch hot-swap SATA/SAS/NVMe drive bays
M.2 Slots2 x M.2 (for OS or cache drives)
Onboard LANDual 10GbE (Intel)
ManagementASUS ASMB11-iKVM BMC; IPMI 2.0; Redfish API
Power SupplyDual redundant 80 PLUS Titanium PSUs
USB PortsFront: 1 x USB 3.2 Gen 1 Type-A; Rear: 2 x USB 3.2 Gen 1 Type-A
Display Output1 x VGA (rear)
Operating System SupportWindows Server, Red Hat Enterprise Linux, Ubuntu Server, VMware ESXi
DimensionsCompliant with standard 4U EIA-310 rack specification

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandASUS
CategoryGPUs
SKUESC4000H-E12
Part NumberESC4000H-E12
ConditionNew
Manufacturer Part NumberESC4000H-E12
Form Factor4U Rackmount
CPU SupportDual Intel Xeon Scalable 4th Generation (Sapphire Rapids) processors
ChipsetIntel C741
CPU Sockets2 x LGA4677
Memory Slots32 x DIMM slots (16 per CPU)
Memory TypeDDR5 ECC Registered (RDIMM / 3DS RDIMM)
Max Memory Capacity4TB (with 3DS RDIMMs)
GPU Slots4 x PCIe 5.0 x16 full-length, double-width GPU slots
PCIe Expansion1 x OCP 3.0 mezzanine slot
Storage Bays8 x 2.5-inch hot-swap SATA/SAS/NVMe drive bays
M.2 Slots2 x M.2 (for OS or cache drives)
Onboard LANDual 10GbE (Intel)
ManagementASUS ASMB11-iKVM BMC; IPMI 2.0; Redfish API
Power SupplyDual redundant 80 PLUS Titanium PSUs
USB PortsFront: 1 x USB 3.2 Gen 1 Type-A; Rear: 2 x USB 3.2 Gen 1 Type-A
Display Output1 x VGA (rear)
Operating System SupportWindows Server, Red Hat Enterprise Linux, Ubuntu Server, VMware ESXi
DimensionsCompliant with standard 4U EIA-310 rack specification

Frequently Asked Questions about ASUS ESC4000H-E12 4-GPU Server

What server platforms accept the ASUS ESC4000H-E12 4-GPU Server?

Reference servers include Dell PowerEdge XE9680 / XE9712, HPE Cray XD670, Lenovo ThinkSystem SR685a / SR675 V3, Supermicro AS-A21GE / SYS-821GE, Gigabyte G593 / G894, ASUS ESC. Share your target platform in the RFQ and we will confirm chassis-to-GPU compatibility and recommended NIC pairing.

How long is the lead time on AI GPUs?

Highly model-dependent. L40S / RTX-class: typically 3-6 weeks. H100/H200/B200 in SXM form factor: 12-16 weeks for whole-platform allocations. We quote genuine-channel ETAs only — no grey-market promises.

Do you supply matched networking (Quantum InfiniBand / Spectrum-X)?

Yes — Omnixon stocks the full NVIDIA networking lineup (Quantum-2 / Quantum-X InfiniBand, Spectrum-X Ethernet, ConnectX NICs, BlueField DPUs) so we can quote a complete training-cluster BOM, not just the GPUs.

Can you help with NVIDIA AI Enterprise licensing?

Yes. We hold genuine-channels for NVIDIA AI Enterprise software subscriptions. Add it to your RFQ and we quote node-aligned licensing along with the hardware.