AMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade

AMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade

Brand: HPE | Category: GPUs

SKU: P53871-B21 | Part #: P53871-B21 | MPN: P53871-B21

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About the AMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade

The AMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade (P53871-B21) is a high-performance accelerator built on AMD's CDNA2 architecture, designed specifically for large-scale HPC and AI/ML workloads in open-standard OCP Accelerator Module (OAM) form factor. Each MI250X package integrates two GPU dies connected via AMD Infinity Fabric, delivering a combined 128GB of High Bandwidth Memory 2e (HBM2e) and exceptional double-precision floating-point throughput suited to the most demanding scientific computing environments.

Engineered for deployment within the HPE Cray EX235a accelerator blade, the MI250X leverages the blade's liquid-cooled infrastructure to sustain peak computational performance at data center scale. The accelerator supports AMD ROCm open software ecosystem, enabling portability of HPC and AI frameworks including TensorFlow, PyTorch, and OpenMP/OpenCL workloads. With support for bfloat16, FP16, FP32, and FP64 precisions, the MI250X addresses the full spectrum from training large language models to running high-fidelity physics simulations.

The MI250X is purpose-built for tightly integrated, rack-scale supercomputing systems and has been deployed in some of the world's leading national laboratory and hyperscale HPC environments. Its OAM form factor and coherent CPU-GPU interconnect via AMD Infinity Fabric links to the host processor enable high-bandwidth, low-latency data movement critical for multi-node distributed computing. Omnixon Global supplies this HPE-branded solution to enterprise, government, and research customers across UAE, GCC, EMEA, and APAC regions.

Ideal for

  • Large-scale AI and deep learning model training, including transformer-based large language models requiring high HBM bandwidth and FP16/BF16 throughput
  • High-performance computing (HPC) scientific simulations such as molecular dynamics, computational fluid dynamics, and climate modeling demanding sustained FP64 performance
  • Multi-node distributed training workloads on HPE Cray EX supercomputing clusters leveraging NVLink-class GPU-to-GPU communication via AMD Infinity Fabric
  • Seismic processing and reservoir simulation in energy sector deployments requiring massive parallel floating-point computation
  • Government and national laboratory research workloads on TOP500-class supercomputers using liquid-cooled HPE Cray EX infrastructure
  • Inference at scale for large AI models in sovereign cloud and enterprise datacenter environments requiring high memory capacity per accelerator

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP53871-B21
Product NameAMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade
GPU ArchitectureAMD CDNA2
Form FactorOCP Accelerator Module (OAM)
Total GPU Memory128 GB HBM2e (2x 64 GB per GCD)
Memory TypeHBM2e
Memory Bandwidth3.2 TB/s aggregate
Compute Dies2 (dual GCD — Graphics Compute Die)
Peak FP64 Performance47.9 TFLOPS
Peak FP64 Vector Performance95.7 TFLOPS
Peak FP32 Performance95.7 TFLOPS
Peak FP16 Performance383 TFLOPS
Peak BF16 Performance383 TFLOPS
Compute Units220 total (110 per GCD)
InterconnectAMD Infinity Fabric (inter-die and host)
Infinity Fabric BandwidthUp to 800 GB/s (inter-die)
Supported PrecisionsFP64, FP32, FP16, BF16, INT8
CoolingLiquid-cooled (HPE Cray EX blade infrastructure)
Compatible PlatformHPE Cray EX235a Accelerator Blade
Software EcosystemAMD ROCm (supports HIP, OpenMP, OpenCL, TensorFlow, PyTorch)

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryGPUs
SKUP53871-B21
Part NumberP53871-B21
ConditionNew
Manufacturer Part NumberP53871-B21
Product NameAMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade
GPU ArchitectureAMD CDNA2
Form FactorOCP Accelerator Module (OAM)
Total GPU Memory128 GB HBM2e (2x 64 GB per GCD)
Memory TypeHBM2e
Memory Bandwidth3.2 TB/s aggregate
Compute Dies2 (dual GCD — Graphics Compute Die)
Peak FP64 Performance47.9 TFLOPS
Peak FP64 Vector Performance95.7 TFLOPS
Peak FP32 Performance95.7 TFLOPS
Peak FP16 Performance383 TFLOPS
Peak BF16 Performance383 TFLOPS
Compute Units220 total (110 per GCD)
InterconnectAMD Infinity Fabric (inter-die and host)
Infinity Fabric BandwidthUp to 800 GB/s (inter-die)
Supported PrecisionsFP64, FP32, FP16, BF16, INT8
CoolingLiquid-cooled (HPE Cray EX blade infrastructure)
Compatible PlatformHPE Cray EX235a Accelerator Blade
Software EcosystemAMD ROCm (supports HIP, OpenMP, OpenCL, TensorFlow, PyTorch)

Frequently Asked Questions about AMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade

What server platforms accept the AMD Instinct MI250X 128GB OAM GPU for HPE Cray EX235a Blade?

Reference servers include Dell PowerEdge XE9680 / XE9712, HPE Cray XD670, Lenovo ThinkSystem SR685a / SR675 V3, Supermicro AS-A21GE / SYS-821GE, Gigabyte G593 / G894, ASUS ESC. Share your target platform in the RFQ and we will confirm chassis-to-GPU compatibility and recommended NIC pairing.

How long is the lead time on AI GPUs?

Highly model-dependent. L40S / RTX-class: typically 3-6 weeks. H100/H200/B200 in SXM form factor: 12-16 weeks for whole-platform allocations. We quote genuine-channel ETAs only — no grey-market promises.

Do you supply matched networking (Quantum InfiniBand / Spectrum-X)?

Yes — Omnixon stocks the full NVIDIA networking lineup (Quantum-2 / Quantum-X InfiniBand, Spectrum-X Ethernet, ConnectX NICs, BlueField DPUs) so we can quote a complete training-cluster BOM, not just the GPUs.

Can you help with NVIDIA AI Enterprise licensing?

Yes. We hold genuine-channels for NVIDIA AI Enterprise software subscriptions. Add it to your RFQ and we quote node-aligned licensing along with the hardware.