AMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus

AMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus

Brand: HPE | Category: GPUs

SKU: P60638-B21 | Part #: P60638-B21 | MPN: P60638-B21

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About the AMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus

The AMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus (P60638-B21) is built on AMD's CDNA2 compute architecture, delivering high-throughput double-precision and matrix compute performance purpose-built for scientific, AI, and data analytics workloads. The MI210 features 64 GB of HBM2e memory with a 500 GB/s memory bandwidth, enabling large-scale model training and simulation workloads that demand both capacity and speed within a standard PCIe form factor compatible with HPE's validated server ecosystem.

Engineered for deployment in HPE ProLiant DL380 Gen10 Plus servers, this GPU option kit has been factory-validated and qualified by HPE to ensure firmware, driver, and thermal compatibility within that platform. The MI210 supports AMD ROCm open-software platform, providing a portable and open ecosystem for HPC and machine learning frameworks including TensorFlow, PyTorch, and OpenCL-compatible scientific applications. With support for PCIe 4.0 x16 connectivity, the accelerator integrates cleanly into modern dual-socket server configurations without requiring proprietary interconnect fabrics.

The MI210 is positioned for enterprise datacenters requiring GPU acceleration at scale across AI inferencing, high-performance computing (HPC) simulations, and large dataset analytics. Its passive cooling design is optimized for rack-mounted datacenter environments where airflow is managed at the chassis level, making it well-suited for dense HPE ProLiant deployments in UAE, GCC, EMEA, and APAC datacenter facilities seeking certified, enterprise-grade GPU compute expansion.

Ideal for

  • Large-scale deep learning model training using PyTorch or TensorFlow on HPE ProLiant DL380 Gen10 Plus servers
  • High-performance computing (HPC) simulations in computational fluid dynamics, molecular dynamics, and finite element analysis
  • AI inferencing for enterprise applications requiring high memory capacity and sustained throughput
  • Big data analytics acceleration across large datasets requiring fast GPU-parallel processing
  • Scientific research workloads leveraging double-precision FP64 compute performance in academic and government datacenter environments
  • Energy sector and engineering simulation workloads demanding validated, rack-mounted GPU accelerators in regulated datacenter infrastructure

Technical specifications

ManufacturerHPE
Manufacturer Part NumberP60638-B21
Product NameAMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus
GPU ArchitectureAMD CDNA2
GPU Memory64 GB HBM2e
Memory Bandwidth500 GB/s
InterfacePCIe 4.0 x16
Form FactorFull-height, full-length (FHFL) passive cooled
FP64 Peak Performance45.3 TFLOPS
FP32 Peak Performance45.3 TFLOPS
Peak FP16 Performance181.0 TFLOPS
Peak BF16 Performance181.0 TFLOPS
Board Power (TDP)300 W
Compute Units104
Compatible ServerHPE ProLiant DL380 Gen10 Plus
Software EcosystemAMD ROCm open software platform
Supported FrameworksTensorFlow, PyTorch, OpenCL
CoolingPassive (datacenter airflow-cooled)
HPE QualificationFactory-integrated option kit, HPE validated and certified for DL380 Gen10 Plus

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryGPUs
SKUP60638-B21
Part NumberP60638-B21
ConditionNew
Manufacturer Part NumberP60638-B21
Product NameAMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus
GPU ArchitectureAMD CDNA2
GPU Memory64 GB HBM2e
Memory Bandwidth500 GB/s
InterfacePCIe 4.0 x16
Form FactorFull-height, full-length (FHFL) passive cooled
FP64 Peak Performance45.3 TFLOPS
FP32 Peak Performance45.3 TFLOPS
Peak FP16 Performance181.0 TFLOPS
Peak BF16 Performance181.0 TFLOPS
Board Power (TDP)300 W
Compute Units104
Compatible ServerHPE ProLiant DL380 Gen10 Plus
Software EcosystemAMD ROCm open software platform
Supported FrameworksTensorFlow, PyTorch, OpenCL
CoolingPassive (datacenter airflow-cooled)
HPE QualificationFactory-integrated option kit, HPE validated and certified for DL380 Gen10 Plus

Frequently Asked Questions about AMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus

What server platforms accept the AMD Instinct MI210 64GB PCIe GPU for HPE ProLiant DL380 Gen10 Plus?

Reference servers include Dell PowerEdge XE9680 / XE9712, HPE Cray XD670, Lenovo ThinkSystem SR685a / SR675 V3, Supermicro AS-A21GE / SYS-821GE, Gigabyte G593 / G894, ASUS ESC. Share your target platform in the RFQ and we will confirm chassis-to-GPU compatibility and recommended NIC pairing.

How long is the lead time on AI GPUs?

Highly model-dependent. L40S / RTX-class: typically 3-6 weeks. H100/H200/B200 in SXM form factor: 12-16 weeks for whole-platform allocations. We quote genuine-channel ETAs only — no grey-market promises.

Do you supply matched networking (Quantum InfiniBand / Spectrum-X)?

Yes — Omnixon stocks the full NVIDIA networking lineup (Quantum-2 / Quantum-X InfiniBand, Spectrum-X Ethernet, ConnectX NICs, BlueField DPUs) so we can quote a complete training-cluster BOM, not just the GPUs.

Can you help with NVIDIA AI Enterprise licensing?

Yes. We hold genuine-channels for NVIDIA AI Enterprise software subscriptions. Add it to your RFQ and we quote node-aligned licensing along with the hardware.