Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch

Brand: Mellanox | Category: Network Switches

SKU: MSB8050-HS2R | Part #: MSB8050-HS2R | MPN: MSB8050-HS2R

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About the Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch

The Mellanox Quantum-2 NDR400 is a high-density spine/leaf InfiniBand switch purpose-built for next-generation AI and high-performance computing (HPC) fabric deployments. With 40 ports of NDR (400 Gbps) connectivity, the MSB8050-HS2R delivers ultra-low latency and deterministic performance required for GPU-accelerated machine learning clusters and large-scale parallel computing environments.

This switch operates as a critical infrastructure component in two-tier or multi-tier Clos fabric topologies, enabling non-blocking bandwidth between compute nodes, storage systems, and accelerators. The architecture supports lossless Ethernet semantics over InfiniBand, ensuring reliable delivery of time-sensitive cluster traffic without application-level retransmission overhead.

Deploy as a spine aggregation layer or leaf-to-spine uplink for modular data center scaling. The MSB8050-HS2R is optimized for sovereign AI infrastructure, research computing centers, and hyperscale GPU training environments where fabric efficiency directly impacts per-dollar compute throughput and model time-to-accuracy.

Ideal for

  • GPU cluster interconnect for distributed deep learning model training and inference at scale
  • High-performance computing (HPC) fabric for scientific simulation, weather modeling, and computational research
  • Real-time analytics and data warehouse query acceleration across disaggregated storage and compute nodes
  • Enterprise AI service fabric for multi-tenant machine learning platform infrastructure
  • Spine aggregation layer in modular 400G+ data center network architectures
  • Low-latency financial modeling and risk simulation compute clusters

Technical specifications

ManufacturerMellanox
BrandMellanox
Model NameQuantum-2 NDR400
Manufacturer Part NumberMSB8050-HS2R
Product CategoryInfiniBand Switch
Switch TypeManaged, non-blocking
Port Count40
Port Speed400 Gbps (NDR)
Port TypeQSFP112
Switching Fabric Capacity16 Tbps
Latency<100 nanoseconds
ArchitectureClos-optimized, spine/leaf
Lossless Protocol SupportInfiniBand, RoCE v2
MemoryDDR4 SDRAM
ManagementWeb UI, SSH, SNMP
Power SupplyDual redundant
AirflowFront-to-back
Form Factor2U rack-mount
Launch DateQ4 2022

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandMellanox
CategoryNetwork Switches
SKUMSB8050-HS2R
Part NumberMSB8050-HS2R
ConditionNew
Model NameQuantum-2 NDR400
Manufacturer Part NumberMSB8050-HS2R
Product CategoryInfiniBand Switch
Switch TypeManaged, non-blocking
Port Count40
Port Speed400 Gbps (NDR)
Port TypeQSFP112
Switching Fabric Capacity16 Tbps
Latency<100 nanoseconds
ArchitectureClos-optimized, spine/leaf
Lossless Protocol SupportInfiniBand, RoCE v2
MemoryDDR4 SDRAM
ManagementWeb UI, SSH, SNMP
Power SupplyDual redundant
AirflowFront-to-back
Form Factor2U rack-mount
Launch DateQ4 2022

Frequently Asked Questions about Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch

What does the Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch do?

The Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch is enterprise networking hardware for data-center, campus, and branch deployments. Common roles include core/distribution switching, server uplinks, top-of-rack fabric, and edge connectivity in mixed Cisco/Arista environments.

What are the headline specs of the Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch?

Key specifications for the Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch: new condition; manufacturer Mellanox; brand Mellanox; model name Quantum-2 NDR400; manufacturer part number MSB8050-HS2R; product category InfiniBand Switch; switch type Managed, non-blocking. Manufacturer part number MSB8050-HS2R. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.

Is the Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch compatible with my infrastructure?

The Mellanox Quantum-2 NDR400 40-Port InfiniBand Switch interoperates with standard switching protocols (LACP, MLAG/VPC, 802.1Q, OSPF/BGP). For specific cross-vendor scenarios — Cisco-to-Arista MLAG peering, fabric integration with Cumulus/SONiC, or migration from legacy Catalyst — our network engineers map a compatibility plan as part of the RFQ.