Brand: HPE | Category: Workstations
SKU: P53566-B21 | Part #: P53566-B21 | MPN: P53566-B21
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The HPE ProLiant ML350 Gen11 is a 2-socket tower server platform engineered for compute-intensive workloads in mid-market and departmental enterprise environments. Built on third-generation EPYC processor architecture, it supports up to 32 DIMM slots with ECC memory, delivering 12-core to 16-core per-socket configurations with up to 12 TFLOPS of peak floating-point performance. The tower form factor enables flexible placement in distributed office and lab environments while maintaining enterprise-class reliability and manageability.
The system accommodates up to eight 3.5-inch hot-swap SAS/SATA drives or six 2.5-inch SFF drives via integrated RAID controllers, with PCIe 5.0 expansion slots supporting GPU acceleration, storage adapters, and network interface cards. Integrated Intelligent Platform Management Interface (IPMI) and Redfish support enable remote out-of-band administration across heterogeneous IT estates.
Gen11 architecture introduces improved thermal efficiency and power delivery to sustained multi-threaded workloads, making the ML350 suitable for engineering simulation, data analytics, visualization-class render nodes, and virtualization host deployments requiring moderate scale and on-premises presence.
| Manufacturer | HPE |
| Model | ProLiant ML350 Gen11 Tower Server |
| ManufacturerPartNumber | P53566-B21 |
| FormFactor | Tower |
| ProcessorSockets | 2 |
| ProcessorFamily | AMD EPYC 8004 Series (Genoa, 3rd-gen EPYC) |
| ProcessorCoresPerSocket | 12–16 cores (dependent on SKU) |
| MaxMemoryCapacity | 4 TB (32 DIMM slots, 128 GB per DIMM) |
| MemoryType | DDR5 RDIMM ECC |
| MemorySpeed | 5600 MHz |
| StorageExpansion | 8× 3.5-inch SAS/SATA hot-swap bays or 6× 2.5-inch SFF bays |
| RAIDController | Smart Array E208i-p SR Gen11 (integrated) |
| PCIExpansion | 3× PCIe 5.0 slots, 1× PCIe 4.0 slot |
| NetworkInterfaces | 2× 1-GbE RJ-45 (integrated); expansion options via daughter card |
| ManagementInterface | IPMI 2.0, Redfish, iLO 6 |
| PowerSupply | 2× hot-plug 800W 80+ Platinum (configurable) |
| ThermalDesign | Tool-less PSU and drive removal, side-access memory/expansion |
| Launched | Q3 2023 |
Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.
| Brand | HPE |
| Category | Workstations |
| SKU | P53566-B21 |
| Part Number | P53566-B21 |
| Condition | New |
| Model | ProLiant ML350 Gen11 Tower Server |
| ManufacturerPartNumber | P53566-B21 |
| FormFactor | Tower |
| ProcessorSockets | 2 |
| ProcessorFamily | AMD EPYC 8004 Series (Genoa, 3rd-gen EPYC) |
| ProcessorCoresPerSocket | 12–16 cores (dependent on SKU) |
| MaxMemoryCapacity | 4 TB (32 DIMM slots, 128 GB per DIMM) |
| MemoryType | DDR5 RDIMM ECC |
| MemorySpeed | 5600 MHz |
| StorageExpansion | 8× 3.5-inch SAS/SATA hot-swap bays or 6× 2.5-inch SFF bays |
| RAIDController | Smart Array E208i-p SR Gen11 (integrated) |
| PCIExpansion | 3× PCIe 5.0 slots, 1× PCIe 4.0 slot |
| NetworkInterfaces | 2× 1-GbE RJ-45 (integrated); expansion options via daughter card |
| ManagementInterface | IPMI 2.0, Redfish, iLO 6 |
| PowerSupply | 2× hot-plug 800W 80+ Platinum (configurable) |
| ThermalDesign | Tool-less PSU and drive removal, side-access memory/expansion |
| Launched | Q3 2023 |