HPE ProLiant ML110 Gen11

Brand: HPE | Category: Servers

SKU: P28481-B21 | Part #: P28481-B21 | MPN: P28481-B21

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About the HPE ProLiant ML110 Gen11

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Virtualisation workloads benefit immediately from the HPE ProLiant ML110 Gen11's single-socket Intel Xeon Scalable 4th Generation (Sapphire Rapids) processor architecture, delivering the processing power and memory bandwidth required for consolidation-heavy enterprise environments. This 4U tower server combines HPE's proven reliability with modern processor efficiency, making it an ideal platform for storage architects and IT procurement teams planning mid-range infrastructure refreshes. The ML110 Gen11 (part number P28481-B21) supports up to 8 DIMM slots of DDR5 memory and offers flexible storage options across 8 LFF (3.5-inch) hot-plug drive bays or 4 SFF (2.5-inch) hot-plug drive bays, accommodating both high-capacity and high-performance storage configurations.

Connectivity and resilience are built in through HPE's Embedded 1GbE 4-port network adapter and support for hot-plug redundant power supplies (configuration dependent), reducing unplanned downtime in production environments. Storage flexibility spans SAS, SATA, and NVMe interfaces via HPE Smart Array controllers, while PCIe Gen 5 expansion slots enable seamless integration of modern I/O adapters. Remote management and security are handled by HPE iLO 6 (Integrated Lights-Out 6) and HPE Silicon Root of Trust, delivering out-of-band control and cryptographic assurance. The tool-less side panel design accelerates maintenance cycles. Operating system support includes VMware vSphere, Microsoft Windows Server, Red Hat Enterprise Linux, and SUSE Linux Enterprise Server, ensuring compatibility across heterogeneous datacentres.

Typical Workloads & Deployment Scenarios

  • Multi-tenant virtualisation clusters running VMware vSphere or Microsoft Hyper-V environments
  • Database workloads and OLAP analytics requiring balanced compute and memory resources
  • Linux-based application servers supporting Red Hat Enterprise Linux or SUSE deployments
  • SAN-attached storage environments leveraging SAS and NVMe mixed-tier configurations
  • High-availability infrastructure with redundant power and out-of-band management via iLO 6

For pricing, configuration options, and technical consultation on the HPE ProLiant ML110 Gen11 (P28481-B21), contact Omnixon Global to request a formal quotation.

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Technical Specifications

BrandHPE
CategoryServers
SKUP28481-B21
Part NumberP28481-B21
ConditionNew
Capacity256GB DDR5
Form FactorTower
InterfaceNVMe
Manufacturer Part NumberP28481-B21
Product LineHPE ProLiant ML110 Gen11
Form FactorTower (4U)
Processor FamilyIntel Xeon Scalable (4th Gen, Sapphire Rapids)
Maximum Processors1
Memory TypeDDR5
Memory Slots8 DIMM slots
Storage Drive Bays (LFF)Up to 8 x LFF (3.5-inch) hot-plug drive bays
Storage Drive Bays (SFF)Up to 4 x SFF (2.5-inch) hot-plug drive bays (configuration dependent)
Supported Drive InterfacesSAS, SATA, NVMe
Storage ControllerHPE Smart Array controller
PCIe GenerationPCIe Gen 5
Network ControllerHPE Embedded 1GbE 4-port network adapter
Remote ManagementHPE iLO 6 (Integrated Lights-Out 6)
SecurityHPE Silicon Root of Trust
Power SupplyHot-plug redundant power supply support (configuration dependent)
Supported Operating SystemsVMware vSphere, Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server
Chassis AccessTool-less side panel access

Frequently Asked Questions about HPE ProLiant ML110 Gen11

What does the HPE ProLiant ML110 Gen11 do?

The HPE ProLiant ML110 Gen11 is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE ProLiant ML110 Gen11?

Key specifications for the HPE ProLiant ML110 Gen11: new condition; category ProLiant Server; processor Intel Xeon E-2400; max cores 8.0; memory 256GB DDR5; storage 8x SFF SATA; gpu support 1x GPU. Manufacturer part number P28481-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.