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HPE ProLiant DL560 Gen12

HPE ProLiant DL560 Gen12

Brand: HPE | Category: Servers

SKU: HP-P77375B21 | Part #: P77375-B21 | MPN: P77375-B21

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About the HPE ProLiant DL560 Gen12

The HPE ProLiant DL560 Gen12 is a 4U four-socket rack server built around Intel Xeon 6 processors with High Bandwidth Memory (HBM), delivering an unprecedented combination of compute density and memory bandwidth in a data-center-optimized chassis. By supporting HBM-equipped Xeon 6 SKUs, the DL560 Gen12 enables system-level memory bandwidth that far exceeds what conventional DDR5 DIMM configurations can achieve, making it purpose-built for workloads where data throughput between CPU and memory is the primary performance constraint. The platform supports multi-socket NUMA topologies across four processor sockets, allowing enterprises to scale both core count and memory capacity simultaneously without fragmenting workloads across separate nodes.

The DL560 Gen12 targets mission-critical in-memory database platforms such as SAP HANA, Oracle Database In-Memory, and Microsoft SQL Server, where terabytes of working data must be accessed at near-cache latencies. The server's architecture also addresses the growing demand for large-scale AI inference consolidation, allowing multiple AI models to reside simultaneously in a unified high-bandwidth memory pool rather than requiring GPU offload for memory-resident inference tasks. HPE's Gen12 platform refresh introduces updated PCIe Gen 5 I/O fabric, enhanced RAS (Reliability, Availability, and Serviceability) features, and tighter integration with HPE iLO 7 for intelligent telemetry-driven management.

From a management and lifecycle perspective, the DL560 Gen12 integrates with HPE GreenLake cloud services, HPE Integrated Smart Update Tools, and the broader HPE OneView infrastructure management ecosystem, enabling automated firmware lifecycle management, predictive health analytics, and policy-driven workload orchestration. The server is designed for enterprise data centers requiring maximum uptime, with redundant power supplies, hot-plug NVMe storage, and advanced memory fault tolerance mechanisms ensuring continuous availability for Tier-1 business applications.

Ideal for

  • SAP HANA scale-up deployments requiring terabyte-scale in-memory OLAP and OLTP processing on a single system image
  • Large-scale AI inference serving where multiple LLM or recommendation models must reside concurrently in high-bandwidth memory for low-latency response
  • Oracle Database In-Memory and Microsoft SQL Server in-memory columnstore workloads demanding sustained multi-TB/s memory bandwidth
  • High-frequency financial analytics and real-time risk calculation engines processing massive in-memory datasets across four NUMA domains
  • Genomics and life sciences bioinformatics pipelines requiring rapid random-access traversal of large reference datasets held entirely in memory
  • Enterprise data warehousing consolidation where multiple analytical workloads are co-located on a single high-memory-bandwidth four-socket platform

Technical specifications

ManufacturerHP (HPE)
Product LineHPE ProLiant DL560 Gen12
Form Factor4U Rack Server
Processor Sockets4 x Intel Xeon 6 (Granite Rapids / Granite Rapids-HBM) LGA7529
Processor SupportIntel Xeon 6 with HBM (High Bandwidth Memory) and standard DDR5 SKUs
CPU HBM Capacity (per socket)Up to 128 GB HBM3 on-package per HBM-enabled Xeon 6 processor
Maximum Installed HBMUp to 512 GB HBM3 aggregate (4 sockets × 128 GB)
DIMM SlotsUp to 96 x DDR5 DIMM slots (24 per socket)
Maximum DDR5 CapacityUp to 24 TB DDR5 RDIMM/MRDIMM (with 256 GB RDIMMs)
Memory SpeedDDR5 up to 6400 MT/s; HBM3 up to 3.6 TB/s aggregate bandwidth (4 sockets)
PCIe VersionPCIe 5.0
PCIe Expansion SlotsUp to 16 x PCIe 5.0 slots (including OCP 3.0 mezzanine)
Storage BaysUp to 24 x NVMe/SAS/SATA SFF hot-plug drive bays
Maximum Internal StorageUp to 184.8 TB NVMe (with high-density NVMe configuration)
Network ControllerHPE OCP 3.0 25/100GbE FlexibleLOM; optional dual-port 100GbE
Management ControllerHPE iLO 7 with embedded health monitoring, predictive analytics, and zero-trust security
Power SuppliesUp to 4 x 2400W Titanium-level (96%+ efficiency) hot-plug redundant PSUs
CoolingHigh-performance hot-plug redundant fans with HPE Thermal Control Engine (TCE)
ChipsetIntel C741 (Birch Stream platform)
BIOS/FirmwareUEFI with HPE Secure Boot and silicon root of trust
RAS FeaturesAdvanced ECC, Memory Fault Tolerant Mode, Post Package Repair, Mirroring, Lockstep
Operating System SupportRed Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere, Windows Server 2025
Management SoftwareHPE iLO 7, HPE OneView, HPE GreenLake, HPE Smart Update Manager (SUM)
Chassis Dimensions4U; standard 19-inch EIA rack compatible
CertificationsSAP HANA Tailored Data Center Integration (TDI) certified, ENERGY STAR, EPEAT

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryServers
SKUHP-P77375B21
Part NumberP77375-B21
ConditionNew
Product LineHPE ProLiant DL560 Gen12
Form Factor4U Rack Server
Processor Sockets4 x Intel Xeon 6 (Granite Rapids / Granite Rapids-HBM) LGA7529
Processor SupportIntel Xeon 6 with HBM (High Bandwidth Memory) and standard DDR5 SKUs
CPU HBM Capacity (per socket)Up to 128 GB HBM3 on-package per HBM-enabled Xeon 6 processor
Maximum Installed HBMUp to 512 GB HBM3 aggregate (4 sockets × 128 GB)
DIMM SlotsUp to 96 x DDR5 DIMM slots (24 per socket)
Maximum DDR5 CapacityUp to 24 TB DDR5 RDIMM/MRDIMM (with 256 GB RDIMMs)
Memory SpeedDDR5 up to 6400 MT/s; HBM3 up to 3.6 TB/s aggregate bandwidth (4 sockets)
PCIe VersionPCIe 5.0
PCIe Expansion SlotsUp to 16 x PCIe 5.0 slots (including OCP 3.0 mezzanine)
Storage BaysUp to 24 x NVMe/SAS/SATA SFF hot-plug drive bays
Maximum Internal StorageUp to 184.8 TB NVMe (with high-density NVMe configuration)
Network ControllerHPE OCP 3.0 25/100GbE FlexibleLOM; optional dual-port 100GbE
Management ControllerHPE iLO 7 with embedded health monitoring, predictive analytics, and zero-trust security
Power SuppliesUp to 4 x 2400W Titanium-level (96%+ efficiency) hot-plug redundant PSUs
CoolingHigh-performance hot-plug redundant fans with HPE Thermal Control Engine (TCE)
ChipsetIntel C741 (Birch Stream platform)
BIOS/FirmwareUEFI with HPE Secure Boot and silicon root of trust
RAS FeaturesAdvanced ECC, Memory Fault Tolerant Mode, Post Package Repair, Mirroring, Lockstep
Operating System SupportRed Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere, Windows Server 2025
Management SoftwareHPE iLO 7, HPE OneView, HPE GreenLake, HPE Smart Update Manager (SUM)
Chassis Dimensions4U; standard 19-inch EIA rack compatible
CertificationsSAP HANA Tailored Data Center Integration (TDI) certified, ENERGY STAR, EPEAT

Frequently Asked Questions about HPE ProLiant DL560 Gen12

What does the HPE ProLiant DL560 Gen12 do?

The HPE ProLiant DL560 Gen12 is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE ProLiant DL560 Gen12?

Key specifications for the HPE ProLiant DL560 Gen12: new condition; manufacturer HP (HPE); product line HPE ProLiant DL560 Gen12; form factor 4U Rack Server; processor sockets 4 x Intel Xeon 6 (Granite Rapids / Granite Rapids-HBM) LGA7529; processor support Intel Xeon 6 with HBM (High Bandwidth Memory) and standard DDR5 SKUs; cpu hbm capacity (per socket) Up to 128 GB HBM3 on-package per HBM-enabled Xeon 6 processor. Manufacturer part number P77375-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.