HPE ProLiant DL384 Gen12 Server with NVIDIA GH200

HPE ProLiant DL384 Gen12 Server with NVIDIA GH200

Brand: NVIDIA | Category: Servers

SKU: P65422-B21 | Part #: P65422-B21 | MPN: P65422-B21

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About the HPE ProLiant DL384 Gen12 Server with NVIDIA GH200

The HPE ProLiant DL384 Gen12 Server integrates NVIDIA's Grace Hopper superchip to deliver a unified platform for large-scale AI inference and generative AI workloads. This 2U dual-socket server combines HPE's enterprise-grade reliability with NVIDIA's latest GPU architecture, enabling organizations to deploy transformer models, large language models, and compute-intensive AI applications at scale.

The Grace Hopper superchip provides 144 Arm-based CPU cores per socket with high-bandwidth memory (HBM3) integrated on-package, delivering substantial improvements in memory bandwidth and computational efficiency. This architecture eliminates traditional CPU-GPU bottlenecks, reducing data movement and enabling rapid model iteration and inference serving.

Designed for enterprises requiring maximum AI inference throughput in production environments, the DL384 Gen12 supports dense multi-GPU configurations alongside HPE's management and security frameworks, making it suitable for mission-critical generative AI deployments, vector database operations, and real-time inference services.

Ideal for

  • Large language model (LLM) inference at enterprise scale with reduced latency
  • Generative AI application serving and fine-tuning operations
  • Real-time recommendation engines and personalization platforms
  • Vector search and semantic analysis for RAG (Retrieval-Augmented Generation) systems
  • Batch processing of transformer models for content generation and data analysis
  • High-performance computing workloads requiring unified memory architecture

Technical specifications

ManufacturerNVIDIA
ModelHPE ProLiant DL384 Gen12 Server with NVIDIA GH200
ManufacturerPartNumberP65422-B21
FormFactor2U dual-socket
ProcessorArchitectureNVIDIA Grace Hopper
ProcessorsPerServer2
CoresPerProcessor144
TotalCores288
ProcessorInstructionSetARMv9
MemoryTypeHBM3 on-package
MaximumMemoryCapacity960 GB per socket
MemoryBandwidthUp to 960 GB/s per socket
PCIeGenerationPCIe 5.0
GPUMemoryConfigurationUnified memory with CPU cores
SystemThermalDesignPower4000W typical
ManagementProcessorHPE iLO 6
RedundancyRedundant hot-swap power supplies
SecurityFeaturesSecure boot, measured boot, TPM 2.0
LaunchQuarter2025-Q2

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandNVIDIA
CategoryServers
SKUP65422-B21
Part NumberP65422-B21
ConditionNew
ModelHPE ProLiant DL384 Gen12 Server with NVIDIA GH200
ManufacturerPartNumberP65422-B21
FormFactor2U dual-socket
ProcessorArchitectureNVIDIA Grace Hopper
ProcessorsPerServer2
CoresPerProcessor144
TotalCores288
ProcessorInstructionSetARMv9
MemoryTypeHBM3 on-package
MaximumMemoryCapacity960 GB per socket
MemoryBandwidthUp to 960 GB/s per socket
PCIeGenerationPCIe 5.0
GPUMemoryConfigurationUnified memory with CPU cores
SystemThermalDesignPower4000W typical
ManagementProcessorHPE iLO 6
RedundancyRedundant hot-swap power supplies
SecurityFeaturesSecure boot, measured boot, TPM 2.0
LaunchQuarter2025-Q2

Frequently Asked Questions about HPE ProLiant DL384 Gen12 Server with NVIDIA GH200

What does the HPE ProLiant DL384 Gen12 Server with NVIDIA GH200 do?

The HPE ProLiant DL384 Gen12 Server with NVIDIA GH200 is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE ProLiant DL384 Gen12 Server with NVIDIA GH200?

Key specifications for the HPE ProLiant DL384 Gen12 Server with NVIDIA GH200: new condition; manufacturer NVIDIA; model HPE ProLiant DL384 Gen12 Server with NVIDIA GH200; manufacturerpartnumber P65422-B21; formfactor 2U dual-socket; processorarchitecture NVIDIA Grace Hopper; processorsperserver 2. Manufacturer part number P65422-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.