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HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU

HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU

Brand: HPE | Category: Servers

SKU: HP-P71702B21 | Part #: P71702-B21 | MPN: P71702-B21

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About the HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU

The HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU (part number P71702-B21) addresses a specific operational need in modern data centres: hosting memory-intensive inference workloads and real-time AI services without sacrificing compute density or thermal management. HPE engineered this 2U platform around the latest Intel Xeon Scalable 6th Generation Granite Rapids processors paired with up to two NVIDIA L40S Ada Lovelace GPUs, each delivering 91.6 TFLOPS of single-precision compute and 362 TOPS of INT8 inference throughput. For infrastructure teams evaluating AI deployment options, this configuration sits between general-purpose CPU-only servers and extreme HPC buildouts, making it a natural fit for enterprises rolling out generative AI inference APIs, content moderation pipelines, or vision-based analytics at scale.

Power delivery and redundancy form the foundation of this design, and they drive the economic case for acquisition. The ProLiant DL380 Gen12 ships with dual redundant HPE Flex Slot Platinum Plus PSUs rated at 1600W or 2000W—a 1+1 configuration that means a single PSU failure does not interrupt workloads, a critical requirement in 24/7 data centres. The 2000W option, paired with the dual L40S GPUs (each consuming 350W) and dual Xeon processors, leaves enough headroom for sustained operations without throttling. Data centre managers care deeply about Power Usage Effectiveness (PUE), and the efficiency rating of these Platinum Plus supplies—typically 94% at full load—directly reduces facility cooling costs. HPE's sizing here reflects real-world experience: two GPUs running at full tilt, dual-socket CPU, and up to 8TB of DDR5 memory require careful power budgeting, and Omnixon Global's customers consistently report that oversized PSUs lower their PUE by 0.02 to 0.04 points across larger deployments.

Memory and storage flexibility distinguish this server in the Gen12 lineup. The 32 DIMM slots accept DDR5 RDIMMs or LRDIMMs, scaling from modest configurations up to 8TB of system memory—a headroom most relevant to teams running large language model inference or multi-tenant serving scenarios where batch sizes drive memory consumption. The storage subsystem accommodates up to 24 small-form-factor NVMe, SAS, or SATA drives, depending on configuration, allowing infrastructure architects to tune the balance between GPU cache, system memory, and persistent model storage. Many installations pair the P71702-B21 with NVMe for model loading and inference log buffering, while keeping hot data on SSDs and archival on SATA—a practical split that HPE supports through its single-chassis design. PCIe Gen5 connectivity ensures the NVIDIA L40S GPUs and storage controllers operate without latency bottlenecks, and the x16 lanes per GPU slot provide full bandwidth utilization for inference frameworks like TensorRT and Triton that saturate memory throughput during batched operations.

Network integration and management software complement the hardware foundation. HPE includes integrated 1Gb Ethernet onboard, but the optional PCIe OCP 3.0 mezzanine slots accept 10GbE, 25GbE, or even 100GbE adapters—a flexibility that enterprises deploying inference clusters across multiple subnets or rack segments find essential. HPE iLO 7, the Integrated Lights-Out management controller, provides secure remote console access, hardware health monitoring, and firmware updates without a separate management network. This matters for distributed teams: a systems administrator in Dubai or an AI infrastructure engineer in Singapore can diagnose GPU memory errors, check thermal thresholds, or redeploy the system without being physically present. HPE's Silicon Root of Trust and TPM 2.0 support also address enterprise security policies that mandate attestation and secure boot—requirements increasingly common in regulated industries. The ProLiant DL380 Gen12 runs Red Hat Enterprise Linux, Ubuntu Server, Windows Server 2022/2025, and VMware vSphere 8.x, with full NVIDIA vGPU, CUDA 12.x, and TensorRT support, so deployment teams face no surprise compatibility gaps when moving from test labs to production.

Physically, the 2U form factor positions the P71702-B21 as an efficient use of rack real estate. At approximately 447mm wide and 700mm deep, it fits into standard 19-inch racks with standard cable routing and airflow planning. Two-socket Xeons, two high-end GPUs, 8TB of memory, and dual redundant 2000W PSUs in 2U is compact enough to allow four units per standard rack without thermal conflicts, yet substantial enough that each server handles meaningful workload density. This density appeals to enterprises that either have limited rack space (common in co-located facilities across the Middle East and Southeast Asia) or want to minimize the number of systems to manage operationally.

Performance Specifications & Inference Workload Positioning

  • Dual NVIDIA L40S GPUs with 48GB GDDR6 ECC memory per GPU; 91.6 TFLOPS FP32 and 362 TOPS INT8 per GPU for real-time inference and content processing
  • Intel Xeon Scalable 6th Generation Granite Rapids dual-socket platform with DDR5 memory, supporting up to 8TB system capacity and 24 storage bays for model caching and log buffering
  • PCIe Gen5 x16 per GPU slot ensures full bandwidth saturation for inference frameworks; dual 1600W or 2000W Platinum Plus redundant PSUs with 94% efficiency lower data centre PUE and operating costs
  • HPE iLO 7 management controller with Silicon Root of Trust, Secure Boot, and TPM 2.0 for remote monitoring, firmware updates, and enterprise security compliance across distributed deployments
  • Native support for NVIDIA CUDA 12.x, TensorRT, vGPU, and Triton Inference Server; compatible with Red Hat Enterprise Linux, Ubuntu Server, Windows Server 2022/2025, and VMware vSphere 8.x
  • Flexible networking: integrated 1Gb Ethernet plus optional OCP 3.0 mezzanine for 10/25/100GbE adapters, enabling integration into heterogeneous data centre networks and multi-tenant serving clusters
  • 2U chassis with configurable storage (NVMe, SAS, SATA), optimized for enterprises deploying generative AI inference APIs, model serving pipelines, and vision analytics at scale without sacrificing rack density

Omnixon Global maintains stock and deployment capabilities for the HPE ProLiant DL380 Gen12 (part number P71702-B21) across the UAE, Saudi Arabia, and wider GCC markets, as well as direct fulfillment to data centres and AI labs in India, Southeast Asia, and Europe. We understand the operational pressures facing infrastructure teams: budget cycles require accurate lead times, deployments cannot wait for slow international channels, and technical support must speak your language. Request a formal quotation for the ProLiant DL380 Gen12 with NVIDIA L40S, and Omnixon Global will connect you directly with HPE engineers for custom configurations, power planning, and rack-level deployment consulting—at no cost. Contact our enterprise solutions team to discuss your inference workload, timeline, and rack constraints.

Technical Specifications

BrandHPE
CategoryServers
SKUHP-P71702B21
Part NumberP71702-B21
ConditionNew
Product LineHPE ProLiant DL380 Gen12
Form Factor2U Rack Server
Launch GenerationGen12 (2025-Q3)
GPU ModelNVIDIA L40S Ada Lovelace
GPU Memory48GB GDDR6 ECC per GPU
Max GPU Count2x NVIDIA L40S (factory-configured)
GPU Compute (FP32)91.6 TFLOPS per L40S
GPU INT8 Inference Throughput362 TOPS per L40S
GPU InterconnectPCIe Gen5 x16 per GPU slot
GPU TDP350W per NVIDIA L40S
Processor PlatformIntel Xeon Scalable 6th Generation (Granite Rapids), dual-socket
Max CPU Sockets2
System Memory TypeDDR5 RDIMM / LRDIMM
Memory Slots32 DIMM slots
Max System MemoryUp to 8TB DDR5
Storage BaysUp to 24x SFF NVMe/SAS/SATA drive bays (configuration-dependent)
PCIe GenerationPCIe Gen5
Network InterfacesIntegrated HPE Ethernet 1Gb 4-port; optional OCP 3.0 10/25/100GbE adapters
Management ControllerHPE iLO 7 (Integrated Lights-Out 7)
Power SupplyDual redundant HPE Flex Slot Platinum Plus 1600W / 2000W PSUs
Operating System SupportRed Hat Enterprise Linux, Ubuntu Server, Windows Server 2022/2025, VMware vSphere 8.x
NVIDIA Software StackNVIDIA vGPU, TensorRT, CUDA 12.x, Triton Inference Server
Security FeaturesHPE Silicon Root of Trust, Secure Boot, TPM 2.0, iLO Security Dashboard
Dimensions (HxWxD)2U; approximately 86.8mm x 447mm x 700mm (chassis depth varies by configuration)

Frequently Asked Questions about HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU

What does the HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU do?

The HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU?

Key specifications for the HPE ProLiant DL380 Gen12 with NVIDIA L40S GPU: new condition; manufacturer HP (Hewlett Packard Enterprise); product line HPE ProLiant DL380 Gen12; form factor 2U Rack Server; launch generation Gen12 (2025-Q3); gpu model NVIDIA L40S Ada Lovelace; gpu memory 48GB GDDR6 ECC per GPU. Manufacturer part number P71702-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.