Brand: HPE | Category: Servers
SKU: HP-S2K20A | Part #: S2K20A | MPN: S2K20A
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The HPE ProLiant Compute XD220 Server (S2K20A) is a high-density, single-socket compute node engineered specifically for scale-out HPC environments, AI inference at the edge, and large-scale modeling and simulation clusters. Built on HPE's XD (Extreme Density) architecture, it slots into HPE's multi-node chassis infrastructure, delivering exceptional compute density without compromising individual node manageability or performance. The node supports AMD EPYC processors and is optimized to maximize core counts and memory bandwidth within a thermally and mechanically constrained high-density form factor.
The XD220 is designed to be deployed in large quantities within HPE's ProLiant XD chassis, enabling organizations to build tightly coupled compute clusters with reduced cabling overhead, simplified rack management, and centralized power and cooling infrastructure. Each node maintains independent identity and management through HPE iLO, preserving granular monitoring and firmware control at the node level even within a shared chassis environment. This architecture is particularly well suited to workloads that require many parallel, independent compute tasks running simultaneously across dozens or hundreds of nodes.
Target deployments include university research computing centers, national laboratories, financial risk modeling farms, computational fluid dynamics pipelines, seismic processing environments, and enterprise AI/ML training and inference infrastructure. The ProLiant Compute XD220 is a component of HPE's broader high-performance computing portfolio and is supported under HPE's standard enterprise support services framework, integrating with HPE OneView and HPE Insight Cluster Management Utility for orchestration at scale.
| Manufacturer | HP |
| Manufacturer Part Number | S2K20A |
| Product Line | HPE ProLiant XD |
| Form Factor | High-density multi-node compute node |
| Chassis Compatibility | HPE ProLiant XD chassis |
| Processor Socket | 1 x AMD EPYC (single-socket) |
| Processor Family | AMD EPYC 9004 Series (Genoa) |
| Maximum Processor Cores | Up to 96 cores per node (processor-dependent) |
| Memory Type | DDR5 |
| Memory Slots | 12 x DIMM slots per node |
| Maximum Memory | 1.5TB DDR5 per node |
| Storage Support | NVMe SSD via M.2 or front-accessible drive bays |
| Network | Integrated high-speed fabric connectivity via chassis midplane |
| Management | HPE Integrated Lights-Out (iLO) per node |
| Software Integration | HPE OneView, HPE Insight Cluster Management Utility (CMU) |
| Operating System Support | RHEL, SLES, Ubuntu, Windows Server (selected versions) |
| Power | Shared chassis power infrastructure with per-node power management |
| Security | HPE Silicon Root of Trust, secure boot, node-level firmware integrity |
Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.
| Brand | HPE |
| Category | Servers |
| SKU | HP-S2K20A |
| Part Number | S2K20A |
| Condition | New |
| Manufacturer Part Number | S2K20A |
| Product Line | HPE ProLiant XD |
| Form Factor | High-density multi-node compute node |
| Chassis Compatibility | HPE ProLiant XD chassis |
| Processor Socket | 1 x AMD EPYC (single-socket) |
| Processor Family | AMD EPYC 9004 Series (Genoa) |
| Maximum Processor Cores | Up to 96 cores per node (processor-dependent) |
| Memory Type | DDR5 |
| Memory Slots | 12 x DIMM slots per node |
| Maximum Memory | 1.5TB DDR5 per node |
| Storage Support | NVMe SSD via M.2 or front-accessible drive bays |
| Network | Integrated high-speed fabric connectivity via chassis midplane |
| Management | HPE Integrated Lights-Out (iLO) per node |
| Software Integration | HPE OneView, HPE Insight Cluster Management Utility (CMU) |
| Operating System Support | RHEL, SLES, Ubuntu, Windows Server (selected versions) |
| Power | Shared chassis power infrastructure with per-node power management |
| Security | HPE Silicon Root of Trust, secure boot, node-level firmware integrity |
The HPE ProLiant Compute XD220 Server is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.
Key specifications for the HPE ProLiant Compute XD220 Server: new condition; manufacturer HP; manufacturer part number S2K20A; product line HPE ProLiant XD; form factor High-density multi-node compute node; chassis compatibility HPE ProLiant XD chassis; processor socket 1 x AMD EPYC (single-socket). Manufacturer part number S2K20A. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.