Brand: HPE | Category: Servers
SKU: HPE-P48405-B21 | Part #: P48405-B21 | MPN: P48405-B21
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The HPE P48405-B21 is a 4U tower server built on dual socket Intel LGA4677 architecture, designed for organizations requiring high-density compute in a compact footprint. This HPE ProLiant ML350 Gen11 Small Form Factor (SFF) system supports Intel Xeon Scalable 4th Generation (Sapphire Rapids) processors and the Intel C741 chipset, delivering enterprise-grade performance for mission-critical workloads. The system accommodates up to 16 DIMM slots of DDR5 RDIMM or LRDIMM memory operating at speeds up to 4800 MT/s, while PCIe 5.0 connectivity ensures future-ready I/O bandwidth for accelerators and storage expansion. As a Configure-to-Order platform, the P48405-B21 arrives without pre-configured processors, memory, storage controllers, network interfaces, or power supplies—allowing IT procurement teams to specify exact components matching their workload requirements and budget constraints.
Enterprise data center managers, storage architects, and virtualization teams select the HPE ProLiant ML350 Gen11 when consolidating workloads onto reliable, manageable infrastructure. HPE's integrated Lights-Out 6 (iLO 6) management controller provides remote administration, monitoring, and troubleshooting capabilities, while Silicon Root of Trust and Secure Boot enhance security posture. The server supports HPE Smart Array storage controllers (MR or SR series, ordered separately), flexible networking options configured at order time, and HPE Flex Slot power supplies. Operating system compatibility spans Microsoft Windows Server, Red Hat Enterprise Linux, VMware vSphere, and SUSE Linux Enterprise Server, making this platform adaptable to diverse IT environments. HPE OneView, iLO Amplifier Pack, and Agentless Management tools streamline fleet-wide provisioning and lifecycle operations.
Omnixon Global specializes in matching enterprise hardware specifications to your exact infrastructure needs. To configure your HPE P48405-B21 system with the processors, memory, storage, networking, and power options required for your deployment, submit a detailed Request for Quote through our technical sales team today.
| Brand | HPE |
| Category | Servers |
| SKU | HPE-P48405-B21 |
| Part Number | P48405-B21 |
| Condition | New |
| Form Factor | Tower |
| Interface | Configure-to-Order base — CPU/RAM/storage selectable |
| Manufacturer Part Number | P48405-B21 |
| Product Line | HPE ProLiant ML350 Gen11 |
| Form Factor | Tower (4U) |
| Drive Bay Configuration | Small Form Factor (SFF) |
| Processor Socket | Dual Socket Intel LGA4677 |
| Supported Processor Family | Intel Xeon Scalable 4th Generation (Sapphire Rapids) |
| Chipset | Intel C741 |
| Memory Type | DDR5 RDIMM / LRDIMM |
| Memory Slots | 16 DIMM slots |
| Memory Speed Support | Up to 4800 MT/s |
| PCIe Generation | PCIe 5.0 |
| Management Controller | HPE iLO 6 (Integrated Lights-Out 6) |
| Storage Controller Options | HPE Smart Array controllers (MR or SR series, configured separately) |
| Network Interface | Configured to order; embedded or add-in NIC options available |
| Power Supply | Configured to order; HPE Flex Slot power supply options supported |
| Operating System Support | Microsoft Windows Server, Red Hat Enterprise Linux, VMware vSphere, SUSE Linux Enterprise Server |
| Configuration Type | Configure-to-Order (CTO) — processor, memory, storage, and power not included |
| Security Features | HPE Silicon Root of Trust, Secure Boot, iLO 6 integrated management security |
| Management Software Compatibility | HPE OneView, HPE iLO Amplifier Pack, HPE Agentless Management |
The HPE P48405-B21 - HPE ProLiant ML350 Gen11 SFF Configure-to-Order Server is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. Its Tower / 4U form factor fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.
Key specifications for the HPE P48405-B21 - HPE ProLiant ML350 Gen11 SFF Configure-to-Order Server: form factor Tower / 4U; interface Configure-to-Order base — CPU/RAM/storage selectable; 3 years HPE Foundation Care (default; extendable to 5 years) support; new condition. Manufacturer part number P48405-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.