HPE Cray Supercomputing EX4252 Blade

HPE Cray Supercomputing EX4252 Blade

Brand: HPE | Category: Servers

SKU: HP-P76210B21 | Part #: P76210-B21 | MPN: P76210-B21

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About the HPE Cray Supercomputing EX4252 Blade

The HPE Cray Supercomputing EX4252 Blade is a purpose-built high-performance compute blade designed for integration within the HPE Cray EX supercomputing platform. It features dual AMD EPYC processors from the latest generation, delivering exceptional core counts and memory bandwidth optimized for massively parallel scientific and engineering workloads. The blade architecture leverages HPE's direct liquid cooling (DLC) technology, enabling full thermal management without air-cooling overhead, which allows extreme compute density within standard HPE Cray EX cabinets.

The EX4252 is architected to support the most demanding HPC, AI, and data-intensive simulation workloads at scale. Each blade slot supports high-speed PCIe fabric interconnects and is compatible with the HPE Slingshot high-performance network fabric, delivering low-latency, high-bandwidth communication between compute nodes essential for tightly coupled parallel applications such as computational fluid dynamics, molecular dynamics, and climate modeling simulations.

Notable for its power efficiency per FLOP and its rack-level density, the EX4252 integrates seamlessly with the HPE Performance Cluster Manager and Cray System Management software stack. Operators benefit from unified telemetry, workload scheduling via native integration with industry-standard job schedulers, and deep firmware-level monitoring. The blade is designed to meet the infrastructure requirements of national laboratories, academic research institutions, defense agencies, and large enterprise HPC centers deploying multi-petaflop environments.

Ideal for

  • Large-scale climate and weather modeling simulations requiring sustained petaflop-class compute throughput across thousands of cores
  • Computational fluid dynamics (CFD) workloads in aerospace and automotive engineering demanding tightly coupled MPI parallel execution
  • AI and deep learning training at scale using distributed frameworks such as PyTorch and TensorFlow across hundreds of liquid-cooled blade nodes
  • Genomics and bioinformatics pipelines processing massive datasets in life sciences research environments requiring high memory bandwidth
  • Nuclear and materials science simulations at national laboratories and government research agencies needing extreme floating-point performance density
  • Seismic data processing and reservoir modeling in energy sector HPC clusters requiring high core counts and fast intra-blade memory throughput

Technical specifications

ManufacturerHP
Product LineHPE Cray Supercomputing EX Series
ModelEX4252 Blade
Form FactorHigh-density compute blade for HPE Cray EX cabinet
Processors SupportedDual AMD EPYC (Genoa/Zen 4 architecture)
CPU Cores (per blade)Up to 192 cores (2x 96-core AMD EPYC)
Base / Boost ClockUp to 3.7 GHz boost (workload-dependent)
Memory TypeDDR5 ECC Registered (RDIMM)
Memory Slots24 DIMM slots (12 per processor)
Maximum Memory3 TB DDR5 per blade
Memory BandwidthUp to 921 GB/s aggregate per blade
Cooling TechnologyHPE Direct Liquid Cooling (DLC) — full blade immersion-ready warm-water cooling
Network FabricHPE Slingshot 200Gb/s high-performance interconnect
PCIe GenerationPCIe Gen 5
Local Storage OptionsM.2 NVMe SSD (OS/boot), no spinning media
Blades per CabinetUp to 128 blades in a standard HPE Cray EX cabinet
Management InterfaceHPE Cray System Management (CSM) with BMC / Redfish API
Operating System SupportSUSE Linux Enterprise, Red Hat Enterprise Linux, HPE Cray OS
Workload Scheduler CompatibilitySlurm, PBS Pro, IBM Spectrum LSF
Power InputBlade-level power via HPE Cray EX cabinet PDU (48V DC distribution)
Typical Blade TDPUp to 600W per blade (dual CPU, full memory load)
Security FeaturesSecure Boot, UEFI firmware, TPM 2.0, silicon-level AMD SEV-SNP memory encryption
Launched2025 Q3

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandHPE
CategoryServers
SKUHP-P76210B21
Part NumberP76210-B21
ConditionNew
Product LineHPE Cray Supercomputing EX Series
ModelEX4252 Blade
Form FactorHigh-density compute blade for HPE Cray EX cabinet
Processors SupportedDual AMD EPYC (Genoa/Zen 4 architecture)
CPU Cores (per blade)Up to 192 cores (2x 96-core AMD EPYC)
Base / Boost ClockUp to 3.7 GHz boost (workload-dependent)
Memory TypeDDR5 ECC Registered (RDIMM)
Memory Slots24 DIMM slots (12 per processor)
Maximum Memory3 TB DDR5 per blade
Memory BandwidthUp to 921 GB/s aggregate per blade
Cooling TechnologyHPE Direct Liquid Cooling (DLC) — full blade immersion-ready warm-water cooling
Network FabricHPE Slingshot 200Gb/s high-performance interconnect
PCIe GenerationPCIe Gen 5
Local Storage OptionsM.2 NVMe SSD (OS/boot), no spinning media
Blades per CabinetUp to 128 blades in a standard HPE Cray EX cabinet
Management InterfaceHPE Cray System Management (CSM) with BMC / Redfish API
Operating System SupportSUSE Linux Enterprise, Red Hat Enterprise Linux, HPE Cray OS
Workload Scheduler CompatibilitySlurm, PBS Pro, IBM Spectrum LSF
Power InputBlade-level power via HPE Cray EX cabinet PDU (48V DC distribution)
Typical Blade TDPUp to 600W per blade (dual CPU, full memory load)
Security FeaturesSecure Boot, UEFI firmware, TPM 2.0, silicon-level AMD SEV-SNP memory encryption
Launched2025 Q3

Frequently Asked Questions about HPE Cray Supercomputing EX4252 Blade

What does the HPE Cray Supercomputing EX4252 Blade do?

The HPE Cray Supercomputing EX4252 Blade is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE Cray Supercomputing EX4252 Blade?

Key specifications for the HPE Cray Supercomputing EX4252 Blade: new condition; manufacturer HP; product line HPE Cray Supercomputing EX Series; model EX4252 Blade; form factor High-density compute blade for HPE Cray EX cabinet; processors supported Dual AMD EPYC (Genoa/Zen 4 architecture); cpu cores (per blade) Up to 192 cores (2x 96-core AMD EPYC). Manufacturer part number P76210-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.