Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router
Brand: Cisco | Category: Network Equipment
SKU: CSC-ISR4221K9 | Part #: ISR4221/K9 | MPN: ISR4221/K9
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About the Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router
The Cisco ISR 4221 is a compact SD-WAN–capable router engineered for branch offices and remote sites demanding secure, reliable connectivity. With a maximum throughput of 75 Mbps when security services are enabled and 35 Mbps in base configuration, the ISR4221/K9 delivers efficient performance across distributed enterprise networks. This desktop or 1U rack-mountable device features 2 built-in Gigabit Ethernet ports for WAN and LAN connectivity, supported by dedicated management interfaces including 1 RJ-45 console port, 1 RJ-45 auxiliary port, and 1 USB Type-A management connection. The router incorporates 1 NIM expansion slot and 1 SM expansion slot, enabling customization for evolving network demands. Running Cisco IOS XE, it natively supports Cisco IOS XE SD-WAN and Viptela deployments, making it ideal for organizations transitioning to software-defined networking architectures.
Network engineers and IT procurement teams select the Cisco ISR 4221 for its robust IPsec VPN capabilities—supporting up to 250 IPsec tunnels with throughput of 100 Mbps—and its hardware encryption acceleration featuring AES and 3DES algorithms. The device arrives with 4 GB of default DRAM, expandable to 8 GB, and 4 GB of flash storage, backed by 1 USB 3.0 slot for external storage flexibility. Its internal AC power supply operates across standard 100–240V AC input, ensuring compatibility with global power infrastructure. This combination of expansion capacity, encryption performance, and SD-WAN readiness positions the ISR 4221 as a cost-effective choice for enterprises building resilient, secure branch networks without over-provisioning resources.
Omnixon Global stocks the Cisco ISR 4221 (part number ISR4221/K9) for immediate distribution across the UAE and regional markets. Whether you require units for branch deployments, network refreshes, or pilot SD-WAN initiatives, our enterprise IT hardware team is ready to support your requirements. Submit your RFQ to Omnixon Global today and discover competitive pricing, expedited fulfillment, and technical consultation tailored to your network infrastructure goals.
Technical Specifications
| Brand | Cisco |
| Category | Network Equipment |
| SKU | CSC-ISR4221K9 |
| Part Number | ISR4221/K9 |
| Condition | New |
| Form Factor | Rack-Mount |
| Manufacturer Part Number | ISR4221/K9 |
| Product Series | Cisco ISR 4000 |
| Product Model | ISR 4221 |
| Form Factor | Desktop / 1U Rack-Mountable |
| WAN/LAN Ports (Built-in) | 2 x Gigabit Ethernet (RJ-45) |
| Management Port | 1 x RJ-45 Console, 1 x RJ-45 Auxiliary, 1 x USB Type-A (management) |
| NIM Expansion Slots | 1 |
| SM Expansion Slots | 1 |
| Maximum Throughput (Security Services Enabled) | 75 Mbps |
| Maximum Throughput (Base) | 35 Mbps |
| IPsec VPN Throughput | 100 Mbps |
| Maximum IPsec Tunnels | 250 |
| Operating System | Cisco IOS XE |
| SD-WAN Support | Yes (Cisco IOS XE SD-WAN / Viptela) |
| Hardware Encryption Acceleration | Yes (AES, 3DES) |
| DRAM (Default / Maximum) | 4 GB / 8 GB |
| Flash Storage (Default) | 4 GB |
| USB Storage Slot | 1 x USB 3.0 |
| Power Supply | Internal AC Power Supply, 100–240V AC |
| Power Consumption (Maximum) | 50W |
| Operating Temperature | 0°C to 40°C (32°F to 104°F) |
| Dimensions (H x W x D) | 1.72 x 13.5 x 11.6 in (4.37 x 34.29 x 29.46 cm) |
| Routing Protocols Supported | OSPF, EIGRP, BGP, IS-IS, RIP, Static Routing, MPLS |
Frequently Asked Questions about Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router
What does the Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router do?
The Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router is enterprise networking hardware for data-center, campus, and branch deployments. Common roles include core/distribution switching, server uplinks, top-of-rack fabric, and edge connectivity in mixed Cisco/Juniper/Arista environments.
Is the Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router compatible with my infrastructure?
The Cisco ISR 4221 ISR4221/K9 Cisco ISR 4000 series router interoperates with standard switching protocols (LACP, MLAG/VPC, 802.1Q, OSPF/BGP). For specific cross-vendor scenarios — Cisco-to-Arista MLAG peering, fabric integration with Cumulus/SONiC, or migration from legacy Catalyst — our network engineers map a compatibility plan as part of the RFQ.