ASUS Hyper M.2 x16 Gen5 Card

ASUS Hyper M.2 x16 Gen5 Card

Brand: ASUS | Category: Storage Systems

SKU: ASUS-HYPERM2X16GEN5CARD | Part #: HYPER-M.2-X16-GEN5-CARD | MPN: HYPER-M.2-X16-GEN5-CARD

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About the ASUS Hyper M.2 x16 Gen5 Card

The ASUS Hyper M.2 x16 Gen5 Card is a high-density NVMe expansion solution engineered to unlock the full throughput potential of PCIe 5.0 platforms. Accommodating up to four M.2 2280/2260/2242/22110 NVMe SSDs simultaneously via a single PCIe 5.0 x16 host slot, the card bifurcates the x16 link into four independent x4 channels, each delivering up to 14 GB/s—yielding a theoretical aggregate bandwidth of approximately 56 GB/s when populated with Gen5 NVMe drives. This architecture eliminates the bottleneck historically imposed by PCIe 4.0 expansion cards and positions the card as the definitive storage accelerator for next-generation workstations and entry-level servers built on Intel or AMD PCIe 5.0-capable platforms.

The card is purpose-built for compute-intensive workloads where storage latency and sustained sequential throughput are mission-critical. Its passive thermal design incorporates an aluminum heatsink array and copper heat-spreader fins across all four M.2 slots, ensuring thermal stability for high-endurance Gen5 drives operating under sustained read/write cycles. ASUS integrates an onboard LED POST status indicator and supports the ASUS HyperConnector mechanism for direct motherboard slot integration, reducing mechanical stress on the PCIe connector under heavy chassis vibration environments.

Compatibility spans AMD Ryzen Threadripper PRO, Intel Core X-series, and Intel Xeon W workstation platforms, as well as server motherboards supporting PCIe 5.0 x16 bifurcation at x4x4x4x4 mode. The card requires no additional drivers on modern operating systems, functioning as a transparent NVMe host adapter recognized natively by Windows Server, Linux kernel 5.x+, and VMware ESXi. Its tool-less M.2 retention mechanism and compact PCIe add-in card form factor simplify drive swap operations in dense workstation builds and short-depth rack deployments alike.

Ideal for

  • AI/ML training infrastructure: Aggregating four PCIe 5.0 NVMe SSDs as a high-bandwidth local scratch tier to feed GPU memory at rates exceeding 50 GB/s, eliminating storage starvation during large-model training runs.
  • Video post-production: Supporting real-time simultaneous playback and rendering of multiple streams of 8K RAW and 12K cinema-grade content by delivering sustained multi-drive sequential read performance in editing workstations.
  • High-frequency financial data processing: Providing ultra-low-latency local NVMe storage for tick-data capture and in-memory database overflow in quantitative trading workstations requiring sub-100 µs storage access.
  • Scientific simulation and HPC: Enabling fast checkpoint-restart operations for computational fluid dynamics, molecular dynamics, and finite element analysis jobs by maximizing local NVMe write bandwidth on single-node workstations.
  • Virtualization host storage: Expanding NVMe capacity and throughput on VMware ESXi or Proxmox hosts to provision multiple high-IOPS virtual disk backends for VDI or database VM workloads without consuming SAS/SATA bandwidth.
  • Software-defined storage node construction: Building high-density NVMe-oF target nodes where the quad-drive array serves as a disaggregated storage backend exposed over RDMA fabric to compute cluster nodes.

Technical specifications

ManufacturerASUS
Product LineHyper Series
ModelHyper M.2 x16 Gen5 Card
Host InterfacePCIe 5.0 x16
PCIe Bifurcation Mode Requiredx4x4x4x4 (BIOS-configured on host motherboard)
Number of M.2 Slots4
Supported M.2 Form Factors2242 / 2260 / 2280 / 22110
M.2 Key TypeM-Key
Supported M.2 ProtocolNVMe (PCIe 5.0 / 4.0 / 3.0 compatible per slot)
Theoretical Aggregate BandwidthUp to ~56 GB/s (4× PCIe 5.0 x4 lanes)
Per-Slot BandwidthUp to ~14 GB/s (PCIe 5.0 x4)
Thermal SolutionAluminum heatsink with copper heat-spreader fins per M.2 slot
Card Form FactorFull-height, full-length (FHFL) PCIe add-in card
PCB LayersHigh-density multilayer PCB with impedance-controlled signal traces
Onboard DiagnosticsLED POST status indicator
RAID SupportSoftware RAID via OS (Windows Storage Spaces, Linux mdadm); hardware RAID dependent on host platform
Driver RequirementDriverless (native NVMe stack); Windows Server 2019/2022, Linux kernel 5.x+, VMware ESXi 7.0+
Compatible PlatformsIntel Core X / Xeon W (PCIe 5.0 enabled); AMD Ryzen Threadripper PRO 7000 series and compatible HEDT/workstation motherboards
M.2 Drive RetentionTool-less screw-free retention mechanism
Slot ReinforcementStainless steel PCIe slot shield
Operating Temperature0°C to 55°C
Launch2025 Q1

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Technical Specifications

BrandASUS
CategoryStorage Systems
SKUASUS-HYPERM2X16GEN5CARD
Part NumberHYPER-M.2-X16-GEN5-CARD
ConditionNew
Product LineHyper Series
ModelHyper M.2 x16 Gen5 Card
Host InterfacePCIe 5.0 x16
PCIe Bifurcation Mode Requiredx4x4x4x4 (BIOS-configured on host motherboard)
Number of M.2 Slots4
Supported M.2 Form Factors2242 / 2260 / 2280 / 22110
M.2 Key TypeM-Key
Supported M.2 ProtocolNVMe (PCIe 5.0 / 4.0 / 3.0 compatible per slot)
Theoretical Aggregate BandwidthUp to ~56 GB/s (4× PCIe 5.0 x4 lanes)
Per-Slot BandwidthUp to ~14 GB/s (PCIe 5.0 x4)
Thermal SolutionAluminum heatsink with copper heat-spreader fins per M.2 slot
Card Form FactorFull-height, full-length (FHFL) PCIe add-in card
PCB LayersHigh-density multilayer PCB with impedance-controlled signal traces
Onboard DiagnosticsLED POST status indicator
RAID SupportSoftware RAID via OS (Windows Storage Spaces, Linux mdadm); hardware RAID dependent on host platform
Driver RequirementDriverless (native NVMe stack); Windows Server 2019/2022, Linux kernel 5.x+, VMware ESXi 7.0+
Compatible PlatformsIntel Core X / Xeon W (PCIe 5.0 enabled); AMD Ryzen Threadripper PRO 7000 series and compatible HEDT/workstation motherboards
M.2 Drive RetentionTool-less screw-free retention mechanism
Slot ReinforcementStainless steel PCIe slot shield
Operating Temperature0°C to 55°C
Launch2025 Q1

Frequently Asked Questions about ASUS Hyper M.2 x16 Gen5 Card

What does the ASUS Hyper M.2 x16 Gen5 Card do?

the ASUS Hyper M.2 x16 Gen5 Card suits enterprise data-center storage tiers — all-flash arrays, hyperconverged storage pools (vSAN, Ceph), database backends, and high-throughput backup repositories. It is supported by major server platforms.

What are the headline specs of the ASUS Hyper M.2 x16 Gen5 Card?

Key specifications for the ASUS Hyper M.2 x16 Gen5 Card: new condition; manufacturer ASUS; product line Hyper Series; model Hyper M.2 x16 Gen5 Card; host interface PCIe 5.0 x16; pcie bifurcation mode required x4x4x4x4 (BIOS-configured on host motherboard); number of m.2 slots 4. Manufacturer part number HYPER-M.2-X16-GEN5-CARD. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.