ASUS ESC4000H-E11 4-GPU Intel Xeon AI Server 4U

ASUS ESC4000H-E11 4-GPU Intel Xeon AI Server 4U

Brand: ASUS | Category: GPUs

SKU: ESC4000H-E11 | Part #: ESC4000H-E11 | MPN: ESC4000H-E11

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About the ASUS ESC4000H-E11 4-GPU Intel Xeon AI Server 4U

The ASUS ESC4000H-E11 is a 4U rack-mounted GPU computing server engineered for demanding AI training, deep learning inference, and high-performance computing workloads in enterprise datacenters. Built on the Intel Xeon Scalable (4th Gen, Sapphire Rapids) processor platform with the Intel C741 chipset, the system accommodates dual processors and provides the PCIe 5.0 fabric bandwidth necessary to sustain peak throughput across up to four double-width GPU accelerators simultaneously. The chassis architecture prioritizes thermal efficiency and signal integrity, making it suitable for sustained 24/7 datacenter operation at full GPU load.

The ESC4000H-E11 supports up to 4 TB of DDR5 ECC RDIMM memory across 32 DIMM slots, delivering the high-capacity, high-bandwidth memory subsystem that modern large-scale AI model training and HPC simulation pipelines require. Storage flexibility is addressed through multiple NVMe and SATA/SAS connectivity options, while dual 10GbE onboard LAN and optional OCP 3.0 mezzanine networking facilitate integration into existing enterprise network infrastructure. Redundant 2+1 or 2+2 hot-swap power supply configurations ensure continuous availability in mission-critical environments.

Designed to support GPU accelerators from major silicon vendors via its full-length, full-height, double-width PCIe 5.0 x16 slots, the ESC4000H-E11 is positioned for AI model development, scientific simulation, video transcoding at scale, and financial analytics acceleration. ASUS ASMB11-iKVM out-of-band management and IPMI 2.0 compliance give datacenter operations teams remote monitoring, power control, and system health visibility without requiring physical access to the server.

Ideal for

  • Large-scale AI and deep learning model training using multi-GPU parallelism across frameworks such as PyTorch and TensorFlow
  • High-performance inference serving for enterprise AI applications requiring low-latency GPU-accelerated response at scale
  • Scientific and engineering simulation workloads including computational fluid dynamics, molecular dynamics, and finite element analysis
  • Large-scale video transcoding, rendering, and media processing pipelines in broadcast and streaming infrastructure
  • Financial services risk modeling, Monte Carlo simulation, and real-time analytics acceleration
  • Virtualized GPU workloads and cloud-native AI platform deployments requiring dense compute in a 4U rack footprint

Technical specifications

ManufacturerASUS
Manufacturer Part NumberESC4000H-E11
Form Factor4U Rack
CPU SupportDual Intel Xeon Scalable 4th Gen (Sapphire Rapids) LGA4677
ChipsetIntel C741
Max CPU TDP Supported350W per processor
Memory Slots32 x DDR5 DIMM slots
Max Memory4 TB DDR5 ECC RDIMM
Memory SpeedUp to DDR5-4800
GPU Slots4 x PCIe 5.0 x16 full-length, full-height, double-width slots
Max GPU Support4 double-width GPU accelerators
Storage Bays8 x 2.5-inch hot-swap SATA/SAS drive bays plus NVMe support
M.2 Slots2 x M.2 (PCIe 5.0 x4 / SATA)
Onboard LANDual 10GbE (Intel X550)
Expansion Slots1 x OCP 3.0 mezzanine slot
ManagementASMB11-iKVM, IPMI 2.0, Redfish API
Power SupplyRedundant hot-swap 80 PLUS Platinum PSUs (2+1 configuration)
Operating Temperature0°C to 35°C
Dimensions (W x D x H)438 x 866 x 175 mm (approx.)

Available from Omnixon Global. Submit an RFQ and our team will confirm configuration and availability for your order.

Technical Specifications

BrandASUS
CategoryGPUs
SKUESC4000H-E11
Part NumberESC4000H-E11
ConditionNew
Manufacturer Part NumberESC4000H-E11
Form Factor4U Rack
CPU SupportDual Intel Xeon Scalable 4th Gen (Sapphire Rapids) LGA4677
ChipsetIntel C741
Max CPU TDP Supported350W per processor
Memory Slots32 x DDR5 DIMM slots
Max Memory4 TB DDR5 ECC RDIMM
Memory SpeedUp to DDR5-4800
GPU Slots4 x PCIe 5.0 x16 full-length, full-height, double-width slots
Max GPU Support4 double-width GPU accelerators
Storage Bays8 x 2.5-inch hot-swap SATA/SAS drive bays plus NVMe support
M.2 Slots2 x M.2 (PCIe 5.0 x4 / SATA)
Onboard LANDual 10GbE (Intel X550)
Expansion Slots1 x OCP 3.0 mezzanine slot
ManagementASMB11-iKVM, IPMI 2.0, Redfish API
Power SupplyRedundant hot-swap 80 PLUS Platinum PSUs (2+1 configuration)
Operating Temperature0°C to 35°C
Dimensions (W x D x H)438 x 866 x 175 mm (approx.)

Frequently Asked Questions about ASUS ESC4000H-E11 4-GPU Intel Xeon AI Server 4U

What server platforms accept the ASUS ESC4000H-E11 4-GPU Intel Xeon AI Server 4U?

Reference servers include Dell PowerEdge XE9680 / XE9712, HPE Cray XD670, Lenovo ThinkSystem SR685a / SR675 V3, Supermicro AS-A21GE / SYS-821GE, Gigabyte G593 / G894, ASUS ESC. Share your target platform in the RFQ and we will confirm chassis-to-GPU compatibility and recommended NIC pairing.

How long is the lead time on AI GPUs?

Highly model-dependent. L40S / RTX-class: typically 3-6 weeks. H100/H200/B200 in SXM form factor: 12-16 weeks for whole-platform allocations. We quote genuine-channel ETAs only — no grey-market promises.

Do you supply matched networking (Quantum InfiniBand / Spectrum-X)?

Yes — Omnixon stocks the full NVIDIA networking lineup (Quantum-2 / Quantum-X InfiniBand, Spectrum-X Ethernet, ConnectX NICs, BlueField DPUs) so we can quote a complete training-cluster BOM, not just the GPUs.

Can you help with NVIDIA AI Enterprise licensing?

Yes. We hold genuine-channels for NVIDIA AI Enterprise software subscriptions. Add it to your RFQ and we quote node-aligned licensing along with the hardware.