HPE ProLiant ML350 Gen12
Brand: HP | Category: Servers
SKU: HP-P77373B21 | Part #: P77373-B21 | MPN: P77373-B21
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About the HPE ProLiant ML350 Gen12
The HPE ProLiant ML350 Gen12 from HP is enterprise-grade Servers hardware built for data centers. HPE ProLiant ML350 Gen12 is a dual-socket tower server engineered for Intel Xeon 6 processors and DDR5 memory, purpose-built for branch office and remote site enterprise workloads. Available in brand new condition. HP servers products are trusted by enterprises and data centers worldwide. Available from Omnixon Global. Contact our sales team to request a quote.
Technical Specifications
| Brand | HP |
| Category | Servers |
| SKU | HP-P77373B21 |
| Part Number | P77373-B21 |
| Condition | New |
| Product Line | HPE ProLiant ML350 Gen12 |
| Form Factor | Tower (5U, convertible to rack with optional kit) |
| Processor Support | Dual Intel Xeon 6 processors (P-core and E-core variants supported) |
| Max Processor Count | 2 sockets |
| Processor TDP Range | Up to 500W TDP per processor (model-dependent) |
| Memory Type | DDR5 RDIMM / LRDIMM |
| Memory Slots | Up to 32 DIMM slots (16 per processor) |
| Max Memory Capacity | Up to 8TB DDR5 (with 256GB LRDIMMs) |
| Memory Speed | Up to 6400 MT/s DDR5 |
| Storage Bays | Up to 12 x LFF (3.5") or up to 24 x SFF (2.5") hot-plug drive bays |
| Storage Controllers | HPE MR Gen12 Smart Array Controllers (PCIe Gen 5.0); HPE NS204i-u NVMe Boot Device |
| NVMe Support | Yes — direct NVMe SSD support via PCIe Gen 5.0 and U.2/U.3 backplanes |
| PCIe Expansion | Up to 8 x PCIe Gen 5.0 slots |
| Networking (Embedded) | HPE Ethernet 1Gb 4-port 331i adapter (embedded); optional FlexibleLOM 10/25/100GbE |
| GPU / Accelerator Support | Up to 2 x double-wide GPUs or FPGA accelerators (slot and power dependent) |
| Power Supply | Hot-plug redundant power supplies; up to 1600W 80 PLUS Titanium efficiency |
| Management | HPE iLO 7 (Integrated Lights-Out 7) with silicon root of trust, Agentless Management Service, REST API, and HPE GreenLake integration |
| Security Features | Silicon Root of Trust, Secure Boot, Runtime Firmware Validation, Cryptographic Module, HPE Server Configuration Lock |
| Operating System Support | Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere ESXi |
| Chassis Dimensions (Tower) | Tower orientation; exact chassis dimensions per HPE QuickSpecs (5U rack equivalent) |
| Thermal Management | High-performance hot-plug fans with HPE Thermal Configuration Tool support |
| Launch Generation | Gen12 Platform (2025-Q4) |
Frequently Asked Questions about HPE ProLiant ML350 Gen12
What does the HPE ProLiant ML350 Gen12 do?
The HPE ProLiant ML350 Gen12 is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.
What are the headline specs of the HPE ProLiant ML350 Gen12?
Key specifications for the HPE ProLiant ML350 Gen12: new condition; manufacturer HP (Hewlett Packard Enterprise); product line HPE ProLiant ML350 Gen12; form factor Tower (5U, convertible to rack with optional kit); processor support Dual Intel Xeon 6 processors (P-core and E-core variants supported); max processor count 2 sockets; processor tdp range Up to 500W TDP per processor (model-dependent). Manufacturer part number P77373-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.