HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)
Brand: AMD EPYC | Category: Servers
SKU: P78522-B21 | Part #: P78522-B21 | MPN: P78522-B21
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About the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)
The HPE ProLiant DL385 Gen12 Server powered by AMD EPYC 9005 Series processors delivers exceptional single-socket density in a compact 2U rack form factor, supporting redundant hot-plug power supplies to minimize operational downtime and optimize total cost of ownership. With PCIe 5.0 connectivity and configurable drive bays supporting up to 24 SFF or 12 LFF storage options across NVMe, SAS, and SATA interfaces, this platform is engineered for I/O-intensive enterprise workloads while maintaining energy efficiency across your data center footprint.
Built on the Zen 5 microarchitecture, the AMD EPYC 9005 Series delivers up to 192 processor cores and features 24 DDR5 RDIMM / 3DS RDIMM memory slots for massive parallel processing capability. The server integrates HPE iLO 7 management, Silicon Root of Trust, and Secure Boot security features, while supporting Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, and VMware vSphere environments. Infrastructure architects and IT procurement teams will appreciate the standard 19-inch EIA-310 rack compatibility and PCIe 5.0 GPU accelerator slot support. HPE FlexibleLOM and OCP 3.0 networking options provide flexible connectivity for hybrid cloud and edge deployments. Part number P78522-B21 is the authoritative reference for procurement and system configuration.
Enterprise Deployment Scenarios
- High-performance compute clusters requiring massive core counts and memory bandwidth for scientific simulation and financial modeling
- Virtualized infrastructure consolidation with vSphere or RHEL environments supporting hundreds of concurrent workloads
- GPU-accelerated AI and machine learning inference leveraging PCIe 5.0 accelerator slots with minimal latency
- Dense storage node deployments combining 24 SFF drive bays with AMD EPYC processing for scale-out analytics platforms
- Multi-tenant cloud and colocation environments benefiting from single-socket economics and integrated iLO 7 lifecycle management
Contact Omnixon Global to request a formal quotation for the HPE ProLiant DL385 Gen12 Server and discuss your specific infrastructure requirements.
Technical Specifications
| Brand | AMD EPYC |
| Category | Servers |
| SKU | P78522-B21 |
| Part Number | P78522-B21 |
| Condition | New |
| Manufacturer Part Number | P78522-B21 |
| Server Model | HPE ProLiant DL385 Gen12 |
| Form Factor | 2U Rack |
| Processor Family | AMD EPYC 9005 Series (Zen 5 microarchitecture) |
| Number of Processor Sockets | 1 (Single Socket) |
| Maximum CPU Cores | Up to 192 cores (AMD EPYC 9005 series, model dependent) |
| Memory Slots | 24 DIMM slots |
| Memory Type | DDR5 RDIMM / 3DS RDIMM |
| PCIe Generation | PCIe 5.0 |
| Storage Interface | NVMe, SAS, SATA |
| Drive Bays | Up to 24 SFF or 12 LFF drive bays (configuration dependent) |
| Network Interface | HPE embedded FlexibleLOM / OCP 3.0 slot |
| Management Controller | HPE iLO 7 |
| Power Supply | Redundant hot-plug power supplies supported |
| GPU/Accelerator Support | PCIe 5.0 GPU accelerator slots supported |
| Operating System Support | Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere |
| Security Features | HPE Silicon Root of Trust, Secure Boot, iLO 7 integrated security |
| Rack Compatibility | Standard 19-inch rack, EIA-310 |
| Product Line | HPE ProLiant Gen12 |
Frequently Asked Questions about HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)
What does the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005) do?
The HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005) is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.
What is the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)?
The HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005) is a brand new servers product manufactured by AMD EPYC. It has the SKU P78522-B21 and part number P78522-B21. This enterprise-grade product is available from Omnixon Global.
What are the headline specs of the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)?
Key specifications for the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005): new condition; processor AMD EPYC 9005; ai optimized Yes. Manufacturer part number P78522-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.
What are the key specifications of the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)?
The key specifications of the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005) include: Processor: AMD EPYC 9005, AI Optimized: Yes. For complete specifications and technical documentation, please contact our sales team.
Where can I buy the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005)?
You can buy the HPE ProLiant DL385 Gen12 Server (AMD EPYC 9005) from Omnixon Global, a trusted enterprise IT hardware supplier. We serve enterprises in over 100 countries. Request a quote through our website or contact our sales team directly.