HPE ProLiant DL380 Gen12

Brand: HP | Category: Servers

SKU: HP-P77371B21 | Part #: P77371-B21 | MPN: P77371-B21

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About the HPE ProLiant DL380 Gen12

The HPE ProLiant DL380 Gen12 from HP is enterprise-grade Servers hardware built for data centers. HPE ProLiant DL380 Gen12 is a 2U dual-socket rack server built on the Intel Xeon 6 platform with PCIe Gen5 and OCP 3.0 networking, engineered for high-density virtualization and AI inference workloads. Available in brand new condition. Available from Omnixon Global — contact our team to request a quote.

Technical Specifications

BrandHP
CategoryServers
SKUHP-P77371B21
Part NumberP77371-B21
ConditionNew
Product LineHPE ProLiant DL380 Gen12
Form Factor2U Rack Server
Processor PlatformIntel Xeon 6 (P-core and E-core variants supported)
Processor Sockets2 x Socket LGA7529
Max CPU Cores (per system)Up to 288 cores (with dual Intel Xeon 6 E-core processors)
Memory TypeDDR5 RDIMM / LRDIMM / 3DS RDIMM
Memory Slots32 DIMM slots (16 per processor)
Max Memory CapacityUp to 8 TB DDR5 (with 256 GB 3DS LRDIMMs)
Memory SpeedUp to 6400 MT/s
PCIe GenerationPCIe Gen5 (primary expansion slots)
PCIe Expansion SlotsUp to 8 PCIe Gen5 slots (configuration dependent)
OCP NetworkingOCP 3.0 mezzanine slot (supports up to 200GbE OCP adapters)
Storage Drive BaysUp to 30 x SFF (2.5") NVMe / SAS / SATA, or up to 12 x LFF (3.5") configurations
Storage ControllerHPE MR Gen12 SAS/SATA/NVMe RAID controller (supports RAID 0/1/5/6/10/50/60)
Internal Storage InterfaceNVMe Gen5, SAS 24Gb, SATA 6Gb
Max Internal Storage CapacityUp to 460 TB raw (all-NVMe SFF configuration)
Onboard Network Ports2 x 1GbE dedicated iLO management port + OCP 3.0 data network
Baseboard Management ControllerHPE iLO 7 with silicon root of trust and zero-trust security architecture
Power Supply OptionsHPE Flex Slot Titanium Plus 800W, 1000W, 1600W, 2000W (80 Plus Titanium); redundant hot-plug capable
Redundant PowerYes, hot-plug redundant PSU (1+1 or 2+2 configuration)
CoolingHot-plug high-performance fans with HPE Smart Cooling; supports rear-door heat exchanger
GPU / Accelerator SupportUp to 4 x double-width PCIe Gen5 GPU accelerators (full-length, full-height)
Chassis Dimensions (H x W x D)86.8 mm x 447 mm x 785 mm (2U, standard rack depth)
Management SoftwareHPE iLO 7, HPE Compute Ops Manager, HPE OneView
Security FeaturesHPE Silicon Root of Trust, Project Aurora runtime firmware verification, Secure Boot, TPM 2.0
OS CertificationsVMware vSphere 9, Red Hat Enterprise Linux 9, Windows Server 2025, SUSE Linux Enterprise Server 15, Red Hat OpenShift

Frequently Asked Questions about HPE ProLiant DL380 Gen12

What does the HPE ProLiant DL380 Gen12 do?

The HPE ProLiant DL380 Gen12 is built for enterprise data-center workloads — virtualization (VMware, Proxmox, Nutanix), private cloud, database hosting, and AI/ML training. It fits standard EIA-310 server racks and supports redundant PSUs and hot-swap drives common in production environments.

What are the headline specs of the HPE ProLiant DL380 Gen12?

Key specifications for the HPE ProLiant DL380 Gen12: new condition; manufacturer HP (Hewlett Packard Enterprise); product line HPE ProLiant DL380 Gen12; form factor 2U Rack Server; processor platform Intel Xeon 6 (P-core and E-core variants supported); processor sockets 2 x Socket LGA7529; max cpu cores (per system) Up to 288 cores (with dual Intel Xeon 6 E-core processors). Manufacturer part number P77371-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.