HPE ProLiant DL380 Gen12 GPU Computing Node

HPE ProLiant DL380 Gen12 GPU Computing Node

Brand: HPE | Category: GPUs

SKU: P71676-B21 | Part #: P71676-B21 | MPN: P71676-B21

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About the HPE ProLiant DL380 Gen12 GPU Computing Node

PCIe Gen5 architecture and redundant high-efficiency hot-plug power supplies determine server chassis and PSU compatibility for demanding compute environments. The HPE ProLiant DL380 Gen12 GPU Computing Node (part number P71676-B21) is a 2U rack server engineered to deliver massive parallel processing power through support for multiple high-performance data center GPUs in both PCIe and SXM form factors. Built on the HPE ProLiant DL380 Gen12 platform, this node pairs dual Intel Xeon Scalable (6th Generation) processors with 32 DIMM slots supporting DDR5 RDIMM and LRDIMM memory, enabling organizations to scale memory-intensive AI, HPC, and analytics workloads without bottlenecking.

The system leverages HPE's comprehensive management and security stack—including iLO 7 (Integrated Lights-Out 7), Silicon Root of Trust, Secure Boot, and TPM 2.0 support—to ensure both operational control and defense-in-depth protection. Storage flexibility comes through HPE MR Gen12 SAS/SATA/NVMe controllers, while networking options span HPE embedded and optional OCP 3.0 adapters with 10/25/100GbE connectivity. High-performance redundant hot-plug fan modules with optimized airflow preserve GPU thermal envelope integrity under sustained compute loads. An AI infrastructure team or HPC operations group will find the DL380 Gen12's certified support for Microsoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, and VMware vSphere delivers broad deployment flexibility alongside ENERGY STAR and RoHS compliance.

Typical Workloads & Deployment Scenarios

  • AI/ML training clusters requiring multi-GPU scaling and high-bandwidth interconnect
  • AI inference acceleration for real-time model serving at data center scale
  • High-performance computing (HPC) simulations and scientific research
  • GPU-accelerated data analytics and big-data transformation pipelines
  • Enterprise data center consolidation with unified compute-GPU resource pooling

To explore HPE ProLiant DL380 Gen12 GPU Computing Node configurations and obtain a formal quote for P71676-B21, please submit your requirements to Omnixon Global.

Technical Specifications

BrandHPE
CategoryGPUs
SKUP71676-B21
Part NumberP71676-B21
ConditionNew
Manufacturer Part NumberP71676-B21
Product LineHPE ProLiant DL380 Gen12
Form Factor2U Rack Server
Processor FamilyIntel Xeon Scalable (6th Generation)
Processor Sockets2
Memory TypeDDR5 RDIMM / LRDIMM
Memory Slots32 DIMM slots
PCIe GenerationPCIe Gen5
GPU SupportMultiple high-performance data center GPUs (PCIe and SXM form factors depending on configuration)
Storage ControllerHPE MR Gen12 SAS/SATA/NVMe controllers supported
NetworkHPE embedded and optional OCP 3.0 adapters; 10/25/100GbE options
ManagementHPE iLO 7 (Integrated Lights-Out 7)
Power SupplyRedundant High Efficiency Hot-Plug power supplies
CoolingHigh-performance redundant hot-plug fan modules; optimized airflow for GPU thermal envelope
Operating System SupportMicrosoft Windows Server, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, VMware vSphere
ChassisHPE ProLiant DL380 Gen12 2U chassis
SecurityHPE Silicon Root of Trust, Secure Boot, TPM 2.0 support
Standards ComplianceENERGY STAR, RoHS
Target WorkloadsAI/ML Training, AI Inference, HPC, GPU-accelerated Data Analytics

Frequently Asked Questions about HPE ProLiant DL380 Gen12 GPU Computing Node

What does the HPE ProLiant DL380 Gen12 GPU Computing Node do?

The HPE ProLiant DL380 Gen12 GPU Computing Node accelerates AI/ML training, inference, scientific HPC, and virtualization (vGPU) workloads. Typical deployments include LLM training clusters, computer-vision pipelines, financial risk modeling, and rendering farms.

What are the headline specs of the HPE ProLiant DL380 Gen12 GPU Computing Node?

Key specifications for the HPE ProLiant DL380 Gen12 GPU Computing Node: new condition; raid support H100; gpu support NVIDIA H200; ai optimized Yes. Manufacturer part number P71676-B21. For the full datasheet with electrical, environmental, and compliance details, contact our pre-sales engineering team.

Is the HPE ProLiant DL380 Gen12 GPU Computing Node compatible with my infrastructure?

The HPE ProLiant DL380 Gen12 GPU Computing Node requires a PCIe Gen4 or Gen5 x16 slot, server power adequate for the card's TDP, and CUDA/ROCm driver support in your hypervisor or bare-metal OS. Sales engineering will confirm chassis fit (1U/2U/4U), PCIe lane count, and PSU headroom before quoting.